Skip to main content
SpringerLink
Log in

Highly specific HPLC method for the determination of theophylline in serum

Hochspezifische HPLC-Methode zur Bestimmung von Theophyllin im Serum

  • Posters
  • High-Pressure Liquid Chromatography
  • Published:
Fresenius' Zeitschrift für analytische Chemie Aims and scope Submit manuscript

Conclusion

Because of its high specifity, accuracy and precision the described HPLC method appears to be very useful for establishing the accuracy of other procedures in comparative studies or as confirmation analysis in cases of suspected interference. For routine monitoring of serum theophylline concentrations this procedure is less suitable due to the relatively short life time of the column. Further studies are in progress to develop a candidate reference method for the determination of theophylline based on this procedure.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Hendeles L, Weinberger M, Johnson G (1978) Clin Pharmacokinetics 3:294–312

    Google Scholar 

  2. Staber G, Busch EW, Koller PU (1982) Med Lab 35:10–13

    Google Scholar 

  3. Haeckel R (1980) J Clin Chem Clin Biochem 18:385–394

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut für Klinische Chemie, Medizinische Hochschule Hannover, D-3000, Hannover 61, Federal Republic of Germany

    G. Schumann, I. Isberner & M. Oellerich

Authors
  1. G. Schumann
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. I. Isberner
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Oellerich
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schumann, G., Isberner, I. & Oellerich, M. Highly specific HPLC method for the determination of theophylline in serum. Z. Anal. Chem. 317, 677 (1984). https://doi.org/10.1007/BF00593837

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00593837

Keywords

Search

Navigation