Abstract
In earlier studies of the stability of sulphadimidine (SDM) during the preparation of raw fermented sausage, some unknown reaction products were observed which have been further studied. Sausages prepared with SDM, and their corresponding brines were examined for the presence of desamino-SDM (DAS) and 4-hydroxy-desamino-SDM (SOH), as they are possible products of the reaction between SDM and the additive nitrite. After extraction, clean-up and solid-phase extraction (SPE) concentration, the compounds were identified by HPLC followed by diode array detection. The presence of SOH and DAS could be demonstrated in both sausage and brine. In sausage 2.5% of SDM was converted to DAS, while only a minor amount (0.1%) was transformed to SOH. In brine approximately 2.5% and 4% of the original amount of SDM was found as DAS and SOH, respectively.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 5 May 1997 / Revised version: 4 July 1997
Rights and permissions
About this article
Cite this article
Smit, L., Haagsma, N. & Ruiter, A. Stability of sulphadimidine during raw fermented sausage preparation: reaction of sulphadimidine with nitrite. Z Lebensm Unters Forsch 206, 94–98 (1998). https://doi.org/10.1007/s002170050221
Issue Date:
DOI: https://doi.org/10.1007/s002170050221