Summary
Attempts were made to study differences in the relative effectiveness of different size ranges of motor axons to Renshaw cells by differential blocking of larger fibers of the gastrocnemius nerve in cats anesthetized with Nembutal.
-
1.
Differential blocking of larger fibers in the nerve was successfully obtained by applying trapezoid wave current to the nerve.
-
2.
It was shown that more than half (58.1%) of the Renshaw cells receive homogeneous inputs from a motor axon collaterals, 25.8% of the cell receive collateral inputs from a certain group of fibers, and 12.5% of the Renshaw cells were activated by “γ range” fibers.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adal, M.N., Barker, D.: Intrafusal branching of fusimotor fibres. J. Physiol. (Lond.) 177, 288–299 (1965)
Bessou, P., Emonet-Denand, P., Laporte, Y.: Motor fibres innervating extrafusal and intrafusal muscle fibres in the cat. J. Physiol. (Lond.) 180, 649–672 (1965)
Boyd, I.A.: Signed contributions to the discussion on muscle spindles. In: Muscular afferents and motor control. Ed. by R. Granit. Stockholm: Almqvist & Wiksell 1966
Curtis, D.R., Phillis, J.W., Watkins, J.C.: Cholinergic and noncholinergic transmission in the mammalian spinal cord. J. Physiol. (Lond.) 158, 296–323 (1961)
Curtis, D.R., Ryall, R.W.: The synaptie excitation of Renshaw cells. Exp. Brain Res. 2, 81–96 (1966)
Eccles, J.C., Eccles, R.M., Iggo, A., Lundberg, A.: Electrophysiological investigations on Renshaw cells. J. Physiol. (Lond.) 159, 461–478 (1961)
Eccles, J.C., Fatt, P., Koketsu, K.: Cholinergic and inhibitory synapses in a pathway from motor-axon collaterals to motoneurones. J. Physiol. (Lond.) 126, 524–562 (1954)
Ellaway, P.H.: Recurrent inhibition of fusimotor neurones exhibiting background discharges in the decerebrate and the spinal cat. J. Physiol. (Lond.) 216, 419–439 (1971)
Frank, K., Fuortes, M.G.F.: Unitary activity of spinal interneurones of cats. J. Physiol. (Lond.) 131, 424–435 (1956)
Haase, J., van der Meulen, J.P.: Effects of supraspinal stimulation on Renshaw cells belonging to extensor motoneurons. J. Neurophysiol. 24, 510–520 (1961)
Haase, J., Vogel, B.: Direkte und indirekte Wirkungen supraspinaler Reizungen auf Renshaw-Zellen. Pflügers Arch. 325, 334–346 (1971)
Henneman, E.: Organization of the spinal cord. In: Medical Physiology, 12th ed., vol. II, pp. 1717–1732. Ed. by V.B. Mountcastle. Saint Louis: C.V. Mosby 1968
Kato, M., Fukushima, K.: Recurrent inhibition of γ motoneurons. J. Physiol. Soc. Japan 35, 504 (1973)
Longo, V.G., Martin, W.R., Unna, K.R.: A pharmacological study on the Renshaw cell. J. Pharmacol. exp. Ther. 129, 61–68 (1960)
MacLean, J.B., Leffman, H.: Supraspinal control of Renshaw cells. Exp. Neurol. 18, 94–104 (1967)
Manfredi, M.: Differential block of conduction of larger fibers in peripheral nerve by direct current. Arch. ital. Biol. 108, 52–71 (1970)
Mendell, L.M., Wall, P.D.: Presynaptic hyperpolarization: a role for the fine afferent fibers. J. Physiol. (Lond.) 172, 274–294 (1964)
Noth, J.: Récurrente Hemmung der Extensor-Fusimotoneurone? Pflügers Arch. 329, 23–33 (1971)
Renshaw, B.: Central effects of centripetal impulses in axons of spinal ventral roots. J. Neurophysiol. 9, 191–204 (1946)
Ryall, R.W., Piercey, M.F., Polosa, C., Goldfarb, J.: Excitation of Renshaw cells in relation to orthodromic and antidromic excitation of motoneurons. J. Neurophysiol. 35, 137–148 (1972)
Ross, H.-G., Cleveland, S., Haase, J.: Quantitative relation of Renshaw cell discharges to monosynaptic reflex height. Pflügers Arch. 332, 73–79 (1972)
Sassen, M., Zimmermann, M.: Differential blocking of myelinated nerve fibres by transient depolarization. Pflügers Arch. 341, 179–195 (1973)
Scheibel, M.E., Scheibel, A.B.: Spinal motoneurons, interneurons and Renshaw cells. A Golgi study. Arch. ital. Biol. 104, 328–353 (1966)
Willis, W.D.: The case for the Renshaw cell. Brain Behav. Evol. 4, 5–52 (1971)
Wilson, V.J.: Regulation and function of Renshaw cell discharge. In: Muscular afferent and motor control. Ed. by R. Granit. Stockholm: Almqvist & Wiksell 1966
Wilson, V.J., Talbot, W.H., Kato, M.: Inhibitory convergence upon Renshaw cells. J. Neurophysiol. 27, 1063–1079 (1964)
Zimmermann, M.: Selective activation of C-fibers. Pflügers Arch. 301, 329–333 (1968)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Kato, M., Fukushima, K. Effect of differential blocking of motor axons on antidromic activation of Renshaw cells in the cat. Exp Brain Res 20, 135–143 (1974). https://doi.org/10.1007/BF00234008
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00234008