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Trigeminal representations of the masticatory and extraocular proprioceptors as revealed by horseradish peroxidase retrograde transport

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Summary

Horseradish peroxidase has been injected in the masticatory and extraocular muscles in newborn and adult cats to identify the cells of origin for the muscle endings.

Labeled motoneurons in the nuclei of the III, IV, V and VI nerves have been observed. They are the parent cells of the motor terminals taking up the enzyme in the muscle injected. Labeled ganglionic cells have been found scattered all along the ipsilateral mesencephalic nucleus of the V nerve after injection of both the jaw closing and the jaw opening muscles. Labeled cells have also been found in the ipsilateral caudal part of the same nucleus after injection of the extraocular muscles. These results are interpreted as due to enzyme uptake by the sensory endings of the muscle studied.

Moreover cell bodies in the semilunar ganglion were found marked for both groups of muscles injected showing a second ganglionic representation for the sensory endings.

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References

  • Alvarado-Mallart, M.R., Batini, C., Buisseret-Delmas, C., Gueritaud, J.P., Horcholle-Bossavit, G., Tyć-Dumont, S.: Mesencephalic projections of the rectus lateralis muscle afferents in the cat. Arch. ital. Biol. 113, 1–20 (1975)

    Google Scholar 

  • Bach-y-Rita, P., Ito, F.: Properties of stretch receptors in cat extraocular muscles. J. Physiol. (Lond.) 186, 663–688 (1966)

    Google Scholar 

  • Batini, C., Buisseret, P., Buisseret-Delmas, C.: Trigeminal pathway of the extrinsic eye muscle afferents in cat. Brain Res. 85, 74–78 (1975)

    Google Scholar 

  • Batini, C., Buisseret, P., Kado, R.T.: Extraocular proprioceptive and trigeminal projections to the Purkinje cells of the cerebellar cortex. Arch. ital. Biol. 112, 1–17 (1974)

    Google Scholar 

  • Batini, C., Buisseret-Delmas, C., Corvisier, J.: Capture et transport de la peroxydase exogène dans les muscles masticateurs. Localisation des motoneurones. C.R. Acad. Sci. (Paris) 280, 2239–2240 (1975)

    Google Scholar 

  • Baum, J.: Beiträge zur Kenntnis der Muskelspindeln. Anat. Hefte, L. Abt. 13, 249–305 (1900)

    Google Scholar 

  • Buisseret, P., Gueritaud, G.P., Horcholle-Bossavit, G., Tyć-Dumont, S.: Projections mésencéphaliques des afférences proprioceptives de la musculature extrinsèque des yeux. J. Physiol. (Paris) 65, 369A (1972)

  • Bunt, A.H., Lund, R.D., Lund, J.S.: Retrograde axonal transport of horseradish peroxidase by ganglion cells of the albino rat retina. Brain Res. 73, 215–228 (1974)

    Google Scholar 

  • Cajal, S., Ramón Y: Histologie du système nerveux de l'homme et des Vertébrés. T. II, 993 pp. Paris: Maloine 1911

    Google Scholar 

  • Cody, F.W.J., Lee, R.W.H., Taylor, A.: A functional analysis of the components of the mesencephalic nucleus of the fifth nerve in the cat. J. Physiol. (Lond.) 226, 249–261 (1972)

    Google Scholar 

  • Cooper, S., Daniel, P.D., Whitteridge, D.: Nerve impulses in the brain stem of the goat. Short latency responses obtained by stretching the extrinsic eye muscles and the jaw muscles. J. Physiol. (Lond.) 120, 471–490 (1953)

    Google Scholar 

  • Cooper, S., Daniel, P.D., Whitteridge, D.: Muscle spindles and other sensory endings in the extrinsic eye muscles. The physiology and anatomy of these receptors and of their connexions with the brain stem. Brain 78, 564–583 (1955)

    Google Scholar 

  • Cooper, S., Fillenz, M.: Afferent discharges in response to stretch from the extraocular muscles of the cat and monkey and the innervation of these muscles. J. Physiol. (Lond.) 127, 400–413 (1955)

    Google Scholar 

  • Corbin, K.B.: Observations on the peripheral distribution of fibers arising in the mesencephalic nucleus of the fifth cranial nerve. J. comp. Neurol. 73, 153–177 (1940)

    Google Scholar 

  • Corbin, K.B., Harrison, F.: Function of mesencephalic root of fifth cranial nerve. J. Neurophysiol. 3, 423–435 (1940)

    Google Scholar 

  • Dault, S.H., Smith, R.D.: A quantitative study of the nucleus of the mesencephalic tract of the trigeminal nerve of the cat. Anat. Rec. 165, 79–87 (1969)

    Google Scholar 

  • Fillenz, M.: Responses in the brain stem of the cat to stretch of extrinsic ocular muscles. J. Physiol. (Lond.) 128, 182–189 (1955)

    Google Scholar 

  • Freeman, W.T.: The relationship of the radix mesencephalica trigemini to the extraocular muscles. Arch. Neurol. Psychiat. (Chic.) 14, 111–113 (1925)

    Google Scholar 

  • Friemann, R.: Untersuchungen über Zahl und Anordnung der Muskelspindeln in den Kaumuskeln des Menchen. Anat. Anz. 100, 18–20 (1954)

    Google Scholar 

  • Gacek, R.R.: Localization of neurons supplying the extraocular muscles in the kitten using horseradish peroxidase. Exp. Neurol. 44, 381–403 (1974)

    Google Scholar 

  • Graybiel, A.M., Hartwieg, E.A.: Some afferent connections of the oculomotor complex in the cat: an experimental study with tracer techniques. Brain Res. 81, 543–551 (1974)

    Google Scholar 

  • Gregor, A.: Ueber die Vertheilung der Muskelspindeln in der Muskulatur des Menschlichen Fötus. Arch. Anat. Physiol., Abt. Jahrg., 112–196 (1904)

  • Harrison, F., Corbin, K.B.: The central pathway for the jaw-jerk. Amer. J. Physiol. 135, 439–445 (1941)

    Google Scholar 

  • Hosokawa, H.: Proprioceptive innervation of striated muscles in the territory of cranial nerves. Tex. Rep. Biol. Med. 19, 405–464 (1961)

    Google Scholar 

  • Huber, G.C.: Sensory nerve terminations in the tendons of the extrinsic eye muscles of the cat. J. comp. Neurol. 10, 152–158 (1900)

    Google Scholar 

  • Hugelin, A., Bonvallet, M.: Tonus cortical et contrôle de la facilitation motrice d'origine réticulaire. J. Physiol. (Paris) 49, 1171–1200 (1957)

    Google Scholar 

  • Jerge, C.R.: Organization and function of the trigeminal mesencephalic nucleus. J. Neurophysiol. 26, 379–382 (1963)

    Google Scholar 

  • Johnston, J.B.: The radix mesencephalica trigemini. J. comp. Neurol. 19, 593–664 (1909)

    Google Scholar 

  • Kidokoro, Y., Kubota, K., Shuto, S., Sumino, R.: Reflex organization of cat masticatory muscles. J. Neurophysiol. 31, 695–708 (1968)

    Google Scholar 

  • Kristensson, K., Olsson, Y.: Retrograde axonal transport of protein. Brain Res. 29, 363–365 (1971)

    Google Scholar 

  • Kristensson, K., Olsson, Y.: Retrograde transport of horseradish peroxidase in transected axons. I. Time relationship between transport and induction of chromatolysis. Brain Res. 79, 101–109 (1974)

    Google Scholar 

  • Kristensson, K., Olsson, Y., Sjöstrand, J.: Axonal uptake and retrograde transport of exogenous proteins in the hypoglossal nerve. Brain Res. 32, 399–406 (1971)

    Google Scholar 

  • Kuypers, H.G.J.M., Kievit, J., Groen-Klevant, A.C.: Retrograde axonal transport of horseradish peroxidase in rat's forebrain. Brain Res. 67, 211–218 (1974)

    Google Scholar 

  • Lavail, J.H., Lavail, M.M.: Retrograde axonal transport in the central nervous system. Science 176, 1416–1417 (1972)

    Google Scholar 

  • Manni, E., Bortolami, R., Desole, C.: Eye muscle proprioception and the semilunar ganglion. Exp. Neurol. 16, 226–236 (1966)

    Google Scholar 

  • Manni, E., Bortolami, R., Desole, C.: Peripheral pathway of eye muscle proprioception. Exp. Neurol. 22, 1–12 (1968)

    Google Scholar 

  • Nauta, H.J.W., Pritz, M.B., Lasek, R.J.: Afferents to the rat caudoputamen studied with horseradish peroxidase. An evaluation of a retrograde neuroanatomical research method. Brain Res. 67, 219–238 (1974)

    Google Scholar 

  • Pearson, A.A.: Further observations on the mesencephalic root of the trigeminal nerve. J. comp. Neurol. 91, 147–194 (1949)

    Google Scholar 

  • Pfaffmann, C.: Afferent impulses from the teeth due to pressure and noxious stimulation. J. Physiol. (Lond.) 97, 207–219 (1939)

    Google Scholar 

  • Sauerland, E.K., Thiele, H.: Presynaptic depolarization of lingual and glossopharyngeal nerve afferents induced by stimulation of trigeminal proprioceptive fibers. Exp. Neurol. 28, 344–355 (1970)

    Google Scholar 

  • Sheinin, J.J.: Studies of the mesencephalic nucleus in the normal and experimental cat. Anat. Rec. 55, 36 (1933)

    Google Scholar 

  • Smith, R.D.: Localization of the neurons innervating tendon spindles of masticatory muscles. Exp. Neurol. 25, 646–655 (1969)

    Google Scholar 

  • Smith, R.D., Marcarian, H.Q.: The neuromuscular spindles of the lateral pterygoid muscle. Anat. Anz. Bd. 120, 47–53 (1967)

    Google Scholar 

  • Szentágothai, J.: Anatomical considerations of monosynaptic reflex arcs. J. Neurophysiol. 11, 445–454 (1948)

    Google Scholar 

  • Taylor, A., Davey, M.R.: Behaviour of jaw muscle stretch receptors during active and passive movements in cats. Nature (Lond.) 220, 301–302 (1968)

    Google Scholar 

  • Thelander, H.E.: The course and distribution of the radix mesencephalica trigemini in the cat. J. comp. Neurol. 37, 207–220 (1924)

    Google Scholar 

  • Warr, W.B.: Localization of olivocochlear neurons by means of retrograde axonal transport of horseradish peroxidase. Anat. Rec. 175, 464 (1973)

    Google Scholar 

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Authors and Affiliations

  1. Laboratoire de Psychophysiologie Sensorielle, Université Paris VI, France

    M. R. Alvarado-Mallart, C. Batini, C. Buisseret-Delmas & J. Corvisier

  2. Laboratoire d'Anatomie Comparée, Université Paris VII, France

    M. R. Alvarado-Mallart, C. Batini, C. Buisseret-Delmas & J. Corvisier

  3. Laboratoire de Physiologie Générale, Université Paris XI, France

    M. R. Alvarado-Mallart, C. Batini, C. Buisseret-Delmas & J. Corvisier

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  1. M. R. Alvarado-Mallart
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  2. C. Batini
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  3. C. Buisseret-Delmas
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  4. J. Corvisier
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Alvarado-Mallart, M.R., Batini, C., Buisseret-Delmas, C. et al. Trigeminal representations of the masticatory and extraocular proprioceptors as revealed by horseradish peroxidase retrograde transport. Exp Brain Res 23, 167–179 (1975). https://doi.org/10.1007/BF00235459

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  • DOI: https://doi.org/10.1007/BF00235459

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