Skip to main content
Log in

Development of spinal motoneuron innervation of the upper limb muscle in the rat

  • Published:
Experimental Brain Research Aims and scope Submit manuscript

Summary

Horseradish peroxidase was injected into the biceps brachii muscle of rats at various stages of development, from 10 days to 50 weeks. The retrogradely labeled neurons were found in the ipsilateral ventro-lateral column of the cervical cord, C4–C8, of all stages studied, but the number of labeled neurons decreased according to exponential curve as the age advanced. A striking finding was that the contralateral ventral horn cells were also labeled in the 10- and 14-day-old rats.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Andrew, W.: The anatomy of aging in man and animals, pp. 218–237. New York, London: Grune & Stratton 1971

    Google Scholar 

  • Brody, H.: Organization of the cerebral cortex. J. Comp. Neurol. 102, 511–556 (1955)

    Google Scholar 

  • Ellis, R.S.: Norms for some structural changes in the human cerebellum from birth to old age. J. Comp. Neurol. 32, 1–33 (1920)

    Google Scholar 

  • Graham, R.C., Karnovsky, M.J.: The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney: Ultra structural cytochemistry by a new technique. J. Histochem. Cytochem. 14, 291–302 (1966)

    Google Scholar 

  • Hughes, A.: Cell degeneration in the lateral ventral horn of Xenopus laevis (Daudin). J. Embryol. Exp. Morph. 9, 269–284 (1961)

    Google Scholar 

  • Inukai, T.: On the loss of Purkinje cells, with advancing age, from the cerebellar cortex of the albino rat. J. Comp. Neurol. 45, 1–31 (1928)

    Google Scholar 

  • Johnson, H.A., Erner, S.: Neuron survival in the aging mouse. Exp. Geront. 7, 111–117 (1972)

    Google Scholar 

  • Kristensson, K., Olsson, Y., Sjöstrand, J.: Axonal uptake and tetrograde transport of exogenous proteins in the hypoglossal nerve. Brain Res. 32, 399–406 (1971)

    Google Scholar 

  • Lavail, J.H., Lavail, M.M.: Retrograde axonal transport in the central nervous system. Science 176, 1416–1417 (1972)

    Google Scholar 

  • Nauta, H.J.W., Pritz, M.B., Lasek, R.J.: Afferents to the rat caudoputamen studied with horseradish peroxidase. An evaluation of a retrograde neuroanatomical research method. Brain Res. 67, 219–238 (1974)

    Google Scholar 

  • Prestige, M.C.: The control of cell number in the lumbar spinal ganglia during the development of Xenopus laevis tadpoles. J. Embryol. Exp. Morph. 17, 453–471 (1967)

    Google Scholar 

  • Prestige, M.C.: Evidence that at least some of the motor nerve cells that die during development have first made peripheral connections. J. Comp. Neurol. 170, 123–134 (1976)

    Google Scholar 

  • Romanes, G.J.: Motor localization and the effects of nerve injury on the ventral horn cells of the spinal cord. J. Anat. 80, 117–131 (1946)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Tada, K., Ohshita, S., Yonenobu, K. et al. Development of spinal motoneuron innervation of the upper limb muscle in the rat. Exp Brain Res 35, 287–293 (1979). https://doi.org/10.1007/BF00236616

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00236616

Key words

Navigation