Summary
In the tangential plane (parallel to the pial surface) dendrites in the primary auditory cortex (A1) of cat were found to exhibit preferentially oriented growth. This was shown by means of a computer microscope study of Golgi-Cox stained neurons as seen in 100 μm and 300 μm thick tangential sections. Two techniques were used to represent the 3-dimensional structure of dendrites: the “dendritic stick” and the “dendritic trumpet”. The former dismembers a dendrite into its individual segments; the latter considers a dendrite as an entity and represents it by its centroid, its moments and the spatial dispersion of its branches. Both statistical and Fourier analyses of the data show that within the tangential plane there is a significant and consistent orientation of the dendritic sticks in a dorso-ventral direction which seems correlated with the cortical isofrequency contours observed in electrophysiological maps of the A1 region. The dendritic trumpet analyses also show a distinctly non-random vertical distribution of pyramidal cell basal dendrites but not of stellate cell dendrites.
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Abeles, M., Goldstein, M.H., Jr.: Responses of single units in the primary auditory cortex of the cat to tones and to tone pairs. Brain Res. 42, 337–352 (1972)
Bruzeau, M., Massa, J., Feld, C.: Calder à saché. Paris: Editions Cercle d'Art 1975
Colonnier, M.: The tangential organization of the visual cortex. J. Anat. 98, 327–344 (1964)
Glaser, E.M., Ruchkin, D.S.: Principles of Neurobiological Signal Analysis. New York: Academic Press 1976
Glaser, E.M., Van der Loos, H.: A semi-automatic computer microscope for the analysis of neuronal morphology. IEEE Trans. Biomed. Eng. BME 12, 22–31 (1965)
Glaser, E.M., Van der Loos, H.: Analysis of thick brain sections by observe-reverse computer microscopy: application of a new, high clarity Golgi. Nissl stain. (Submitted for publication) (1979)
Hellweg, F.C., Koch, R., Vollrath, M.: Representation of the cochlea in the neocortex of guinea pigs. Exp. Brain Res. 29, 467–474 (1977)
Imig, T.J., Adrián, H.D.: Binaural columns in the primary field (A1) of cat auditory cortex. Brain Res. 138, 241–257 (1977)
Jenkins, G.M., Watts, D.G.: Spectral Analysis and its Applications. San Francisco: Holden-Day 1968
Lorente de Nó, R.: Cerebral cortex: Cytoarchitecture. In: Physiology of the nervous system (ed. J.F. Fulton), Chap. 15, pp. 274–301. London: Oxford University Press 1938
Merzenich, M.M., Brugge, J.F.: Representation of the cochlear partition in the superior temporal plane of the macaque monkey. Brain Res. 50, 275–296 (1973)
Merzenich, M.M., Kaas, J.H., Roth, G.L.: Auditory cortex in the grey squirrel: tonotopic organization and architectonic fields. J. Comp. Neurol. 166, 387–401 (1976)
Merzenich, M.M., Knight, P.L., Roth, G.L.: Representation of cochlea within primary auditory cortex in the cat. J. Neurophysiol. 38, 231 (1975)
O'Leary, J.L.: Structure of the area striata of the cat. J. Comp. Neurol. 75, 131 (1941)
Pasternak, J.F., Woolsey, T.A.: On the “selectivity” of the Golgi-Cox method. J. Comp. Neurol. 160, 307–312 (1975)
Rall, W.: Cable properties of dendrites and effects of synaptic location. In: Excitatory Synaptic Mechanisms (eds. P. Andersen and J.K.S. Jansen), pp. 175–187. Oslo: Universitets Forlaget 1970
Rose, J.E.: The cellular structure of the auditory region of the cat. J. Comp. Neurol. 91, 409–440 (1949)
Sholl, D.A.: The Organization of the Cerebral Cortex. London: Methuen 1956
Siegel, S.: Nonparametric Statistics for the Behavioral Sciences. New York: McGraw-Hill 1956
Sousa-Pinto, A.: The structure of the first auditory cortex (A1) in the cat. Arch. Ital. Biol. 111, 112–137 (1973)
Van der Loos, H.: Une combinaison de deux vieilles méthodes histologiques pour le système nerveux central. Monatsschr. Psych. Neurol. 132, 330–334 (1956)
Van der Loos, H.: Dendrodendritische verbindingen in de schors der grote hersenen. Doct. Dissert., Haarlem, Univ. Amsterdam 1959
Van der Loos, H.: “improperly” oriented pyramidal cell in the cerebral cortex and its possible bearing on problems of neuronal growth and cell orientation. Bull. Johns Hopkins Hosp. 117, 228–250 (1965)
Wong, W.C.: The tangential organization of dendrites and axons in three auditory areas of the cat's cerebral cortex. J. Anat. 101, 419–433 (1967)
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Glaser, E.M., Van der Loos, H. & Gissler, M. Tangential orientation and spatial order in dendrites of cat auditory cortex: A computer microscope study of Golgi-impregnated material. Exp Brain Res 36, 411–431 (1979). https://doi.org/10.1007/BF00238513
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DOI: https://doi.org/10.1007/BF00238513