Summary
Experiments were carried out in cats to learn the location of sensory axons from the cornea in the trigeminal nerve root just prior to its entry into the brainstem. HRP injected into the cornea labelled these axons and indicated they were not restricted to the ophthalmic division of the nerve root as had been indicated from previous studies. These findings, if representative of other branches of this nerve, offer a partial explanation for the variable preservation of function following transection of an entire division of the trigeminal nerve root in cases of trigeminal neuralgia.
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References
Arvidsson B (1975) Localization of cat trigeminal ganglion cells innervating dental pulp of upper and lower canines studied by retrograde transport of horseradish peroxidase. Brain Res 99: 135–139
Arvidsson B (1977) Retrograde axonal transport of horseradish peroxidase from cornea to trigeminal ganglion. Acta Neuropath (Berlin) 38: 49–52
Arvidsson J, Gobel S (1981) An HRP study of the central projections of primary trigeminal neurons which innervate tooth pulps in the cat. Brain Res 210: 1–16
Dandy WE (1929) An operation for the cure of tic douloureux: partial section of the sensory root at the pons. Arch Surg 18: 687–734
Dandy WE (1932) The brain. Pract Surg II: 1–682
Davis L, Haven HA (1933) Surgical anatomy of sensory root of trigeminal nerve. A. M. A. Arch Neurol Psychiat 29: 1–18
Emmons W, Rhoton A (1971) Subdivision of the trigeminal sensory root. Experimental study in the monkey. J Neurosurg 35: 585–591
Frazier CH (1925) Subtotal resection of sensory root for relief of major trigeminal neuralgia. Arch Neurol Psychiat 13: 378–384
Gudmundsson K, Rhoton AL, Rushton JG (1971) Detailed anatomy of the intracranial portion of the trigeminal nerve. J Neurosurg 35: 592–600
Jannetta P, Rand RW (1966a) Transtentorial retrogasserian rhizotomy in trigeminal neuralgia by microneurosurgical technique. Bull Los Angeles Neurol Soc 31: 93–99
Jannetta P, Rand RW (1966b) Microanatomy of the trigeminal nerve. Anat Rec 154: 362
Jannetta PJ (1977) Treatment of trigeminal neuralgia by suboccipital and transtentorial cranial operations. Clin Neurosurg 24: 538–549
Kerr FWL (1963) The divisional organization of afferent fibers of the trigeminal nerve. Brain 86: 721–732
LaVail J, LaVail M (1974) The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: a light and electron microscopic study. J Comp Neurol 157: 303–357
Mesulam MM (1976) The blue reaction product in horseradish peroxidase neurohistochemistry: incubation parameters and visibility. J Histochem Cytochem 24: 1273–1280
Mesulam MM (1978) Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction-produce with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem 26: 106–117
Morgan C, Nadelhaft I, deGroat WC (1981) The distribution of visceral primary afferents from the pelvic nerve to Lissauer's tract and the spinal gray matter and its relationship to the sacral parasympathetic nucleus. J Comp Neurol 201: 415–440
Morgan CW, deGroat WC, Nadelhaft I (1986) The spinal distribution of sympathetic preganglionic and visceral primary afferent neurons that send axons into the hypogastric nerves of the cat. J Comp Neurol 243: 23–40
Morgan CW, Nadelhaft I, deGroat WC (1978) Anatomical localization of corneal afferent cells in the trigeminal ganglion. Neurosurgery 2: 252–258
Pelletier V, Poulos D, Lende R (1974) Functional localization in the trigeminal root. J Neurosurg 40: 504–513
Ruskell CL (1974) Ocular fibers of the maxillary nerves in the monkey. J Anat 118: 195–203
Sprague JM, Ha H-C (1964) The terminal fields of dorsal root fibers in the lumbosacral spinal cord of the cat, and the dendritic organization of the motor nuclei. Prog Brain Res 11: 120–154
Vonderahe AR (1928) Corneal and scleral anesthesia of the lower half of the eye in a case of trauma of the superior maxillary nerve. Arch Neurol Psychiat 20: 836
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Morgan, C., Jannetta, P.J. & deGroat, W.C. Organization of corneal afferent axons in the trigeminal nerve root entry zone in the cat. Exp Brain Res 68, 411–416 (1987). https://doi.org/10.1007/BF00248806
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DOI: https://doi.org/10.1007/BF00248806