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Integration konvergierender Afferenzen in der bulbären Formatio Reticularis der Katze

Integration of convergent afferent volleys in the bulbar reticular formation of the cat

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Summary

  1. 1.

    The startle reflex evoked by cutaneous stimulation in cats under chloralose anesthesia is inhibited for more than 200 ms by a conditioning cortical volley. The interaction between the cutaneous and the cortical volley takes place in the bulbar and pontine reticular formation.

  2. 2.

    The startle reflex involves a series of reticular neurones. Resistance to repetitive stimulation has been determined to evaluate the functional localization of each neurone within this polysynaptic path.

  3. 3.

    Inhibition following the cortical volley becomes increasingly more effective along the course of the polysynaptic path and is completed within 5–6 ms. Reticular neurones excited directly by the spino-reticular afferents are not inhibited, thus excluding a presynaptic inhibition of the spinoreticular fibres.

Zusammenfassung

  1. 1.

    Ein konditionierender corticaler Reiz inhibiert den somatischen Startlereflex bei Katzen unter Chloralosenarkose für eine Dauer von mehr als 200 ms. Die Interaktionen zwischen beiden Reizen laufen in der bulbären und pontinen Formatio reticularis ab.

  2. 2.

    Dem Startlereflex liegt eine polysynaptische Erregungsschleife zugrunde, die die bulbäre und pontine Formatio reticularis durchzieht. Die Resistenz der reticulären Neurone gegenüber repetitiver Stimulation wurde als Kriterium ihrer funktionellen Lokalisation auf dem polysynaptischen Reflexbogen gewertet.

  3. 3.

    Die corticale Inhibition wird im Verlaufe der polysynaptischen Erregungsschleife zunehmend stärker. Neurone, die von den Startlereflexafferenzen direkt erregt werden, werden durch den corticalen Reiz nicht inhibiert. Dies schliebt eine präsynaptische Inhibition der reticulopetalen Fasersysteme aus.

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Authors and Affiliations

  1. Max-Planck-Institut für Hirnforschung, Abt. für Allgemeine Neurologie, Köln-Merheim

    K. -A. Hossmann

  2. National Institutes of Health, National Institute of Neurological Diseases and Blindness, Bldg. 36, Room 4 B 22, 20014, Bethesda, Md., USA

    K. -A. Hossmann

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Herrn Prof. P. Buser, Paris, bin ich für die Diskussion des Manuskriptes zu Dank verpflichtet.

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Hossmann, K.A. Integration konvergierender Afferenzen in der bulbären Formatio Reticularis der Katze. Exp Brain Res 7, 143–157 (1969). https://doi.org/10.1007/BF00235440

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  • DOI: https://doi.org/10.1007/BF00235440

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