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Comparative pharmacokinetics of theophylline following two fluoroquinolones co-administration

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Summary

Pretreatment for 3 days with oral ofloxacin or norfloxacin had no significant effect on the disposition of a single i.v. dose the theophylline in healthy volunteers.

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References

  1. Wijnands WJA, Vree TB, Van Herwaarden CLA (1986) The effect of the 4-quinolone enoxacin on plasma theophylline concentrations. Pharm Weekbl [Sci] 8: 42–45

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  3. Pfeifer HJ, Greenblatt DJ, Paul Friendman MD (1979) Effect of three antibiotics on theophylline kinetics. Clin Pharmacol Ther 26: 36–40

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Authors and Affiliations

  1. Departments of Hospital Pharmacy, Tenri Hospital, Tenri, Nara, Japan

    M. Sano, I. Yamamoto, J. Ueda, E. Yoshikawa & H. Yamashina

  2. Nagoya Memorial Hospital, Nagoya, Japan

    M. Goto

Authors
  1. M. Sano
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  2. I. Yamamoto
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  3. J. Ueda
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  4. E. Yoshikawa
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  5. H. Yamashina
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  6. M. Goto
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Sano, M., Yamamoto, I., Ueda, J. et al. Comparative pharmacokinetics of theophylline following two fluoroquinolones co-administration. Eur J Clin Pharmacol 32, 431–432 (1987). https://doi.org/10.1007/BF00543982

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  • DOI: https://doi.org/10.1007/BF00543982

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