Skip to main content
Log in

Effect of ascariasis and its treatment on drug absorption

  • Letter To The Editors
  • Published:
European Journal of Clinical Pharmacology Aims and scope Submit manuscript

Summary

Ascariasis has been reported to impair the absorption of nutrients, vitamin A, and D-xylose, which is corrected on treatment. The effect of ascariasis and its treatment on the absorption of sulphadimidine and isoniazid has been investigated. There was no difference between drug absorption before and after the treatment or in comparison with a normal population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Control of ascariasis (1964) WHO Technical Report Series 277: 1–46

    Google Scholar 

  2. Tripathi K, Gonzales F, Lottero H, Bolanos D (1971) Effect of ascaris infection on human nutrition. Am J Trop Med Hyg 20: 212–218

    Google Scholar 

  3. Mahalanabis O, Jalan KN, Maitra JK, Agarwal SK (1976) Vit A absorption in ascariasis. Am J Clin Nutr 29: 1372–1375

    Google Scholar 

  4. Craig CF, Faust EC (1943) Clinical parasitology. Lea and Febiger, Philadelphia, p 658

    Google Scholar 

  5. Varley H, Gowenlock AH, Beli M (1981) Practical clinical biochemistry, vol. 2, 5th edn. William Heinemann, London, p 347

    Google Scholar 

  6. Rao KVN, Kailasasam S, Menon NK, Radhakrishna S (1971) Inactivation of isoniazid by condensation in a syrup preparation. Bul WHO 45: 625–632

    Google Scholar 

  7. Ellard GA, Gammon PT, Wallace SM (1972) The determination of isoniazid and its metabolites in serum and urine. Biochem J 126: 449–458

    Google Scholar 

  8. Webster LT (1985) Drugs used in chemotherapy of helminthiasis. In: Goodman Gilman A, Goodman LS, Ral TN, Murad F (eds) Pharmacological basis of therapeutics. 7th edn. MacMillan, New York, p 347

    Google Scholar 

  9. Owen RL, Brandborg LL (1983) Parasitic disease. In: Gastrointestinal disease — Pathophysiology, diagnosis and management. Sleisenger MH, Fordtram JS (eds) WB Saunders, Philadelphia, pp 989–1022

    Google Scholar 

  10. Sivkumar B, Reddy V (1975) Absorption of vitamin A in children with ascariasis. Am J Trop Med Hyg 78: 114–118

    Google Scholar 

  11. Tripathi K, Duque E, Bolanos O, Lottero H, Mayoral DG (1972) Malabsorption syndrome in ascariasis. Am J Clin Nutr 25: 1276–1281

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kshirsagar, N.A., Joshi, M.V., Takle, M.R. et al. Effect of ascariasis and its treatment on drug absorption. Eur J Clin Pharmacol 34, 217–219 (1988). https://doi.org/10.1007/BF00614563

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00614563

Key words

Navigation