Summary
A possible pharmacokinetic interaction between theophylline and repirinast has been investigated in asthmatic patients. The kinetics of theophylline was studied in seven adult in-patients given theophylline 400–800 mg b.d. alone and after three weeks of co-administration of repirinast.
There was no effect on the kinetics of the combined treatment.
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Takagi, K., Kuzuya, T., Horiuchi, T. et al. Lack of effect of repirinast on the pharmacokinetics of theophylline in asthmatic patients. Eur J Clin Pharmacol 37, 301–303 (1989). https://doi.org/10.1007/BF00679789
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DOI: https://doi.org/10.1007/BF00679789