Summary
In a class experiment in clinical pharmacology, 12 pharmacy students demonstrated on themselves the anticholinergic effects of benzilonium bromide. Changes in salivary volume and heart rate showed differences in duration of action between two formulations of the drug.
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Quilliam, J.P., Turner, P.: Clinical pharmacology: Its role and its integration into the education of medical students. Lancet1967 II, 1081–1083
Brunk, S.F., Ferguson, R.K., Toubes, D.B., Leaverton, P.F., Nordschow, C.D., Wilson, W.R.: A teaching format in clinical pharmacology: Comparison of two xanthines and a placebo. J. clin. Pharmacol.13, 121–126 (1973)
Herxheimer, A., Haefeli, L.: Human pharmacology of hyoscine butylbromide, Lancet1966 II, 418–421
Glegg, A.M., Turner, P.: Pharmacological studies of fluphenazine and nortriptyline in combination in man. J. Pharm. Pharmacol.23, 133–134 (1971)
Chamberlain, D.A., Turner, P., Sneddon, J.M.: Effects of atropine on heart rate in healthy man. Lancet1967 II, 12–15
Murrin, K.R.: A study of oral atropine in healthy adult subjects. Brit. J. Anaesth.45, 475–480 (1973)
Unna, K.R., Glaser, K., Lipton, E.: Dosage of drugs in infants and children. I: Atropine. Pediatrics6, 197–207 (1950)
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Kingsley, P.J., Turner, P. Class experiment in clinical pharmacology with benzilonium bromide, an anticholinergic drug. Eur J Clin Pharmacol 7, 141–143 (1974). https://doi.org/10.1007/BF00561329
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DOI: https://doi.org/10.1007/BF00561329