Abstract
Serial MRI findings are described in two patients with Reye's syndrome, demonstrating diffuse cortical and white matter changes. In the acute stage, T2-weighted images showed subtle but definite laminar high signal and contrast-enhanced T1-weighted images laminar enhancement, along the entire cerebral cortexbilateraly. In the chronic stage, unenhanced T1-weighted images showed diffuse cortical laminar high signal. These characteristic MRI features seemed very similar to those of laminar cortical necrosis in hypoxic brain damage. MRI also displayed delayed white matter changes with cerebral atrophy.
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Kinoshita, T., Takahashi, S., Ishii, K. et al. Reye's syndrome with cortical laminar necrosis: MRI. Neuroradiology 38, 269–272 (1996). https://doi.org/10.1007/BF00596545
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DOI: https://doi.org/10.1007/BF00596545