Skip to main content
SpringerLink
Log in

A T1-weighted rapid three-dimensional gradient-echo technique (MP-RAGE) in preoperative MRI of intracranial tumours

  • Diagnostic Neuroradiology
  • Published:
Neuroradiology Aims and scope Submit manuscript

Abstract

Oar purpose was to determine the value of a T1-weighted rapid three-dimensional gradientecho technique in preoperative MRI of brain tumours. We examined 30 patients with intracranial tumours who underwent neurosurgery, using T1-wighted magnetisation-prepared rapid gradient-echo (MP-RAGE) and axial T1-weighted spin-echo (SE) sequences, both before and after contrast medium (Gd-DTPA). Signal and contrast behaviour of anatomical and pathological structures were assessed with regions-of-interest (ROI) and visual inspection. Imaging results were compared with operative results. In 5 cases tumours and anatomical structure were segmented in MP-RAGE data sets. The MP-RAGE sequence considerably improved delineation of grey and white matter and small anatomical structures (vessels, cranial nerves), and significantly reduced flow artefacts. Contrast behaviour of tumours was similar with both techniques. Correlation of imaging with the operative results confirmed the reliability of the MP-RAGE sequence. Segmentation of MP-RAGE data sets allows three-dimensional display, which enables one to document the relevant information on a few images in selected cases.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Kramer DM, Schneider JS, Rudin AM, Lauterbur PC (1981) True three-dimensional nuclear magnetic resonance zeugmatographic images of a human brain. Neuroradiology 21:239–244

    Google Scholar 

  2. Haase A, Frahm J, Matthaei D, Hänicke W, Merboldt KD (1986) FLASH imaging: rapid NMR imaging using low flipangle pulses. J Magn Reson 67:258–266

    Google Scholar 

  3. Frahm J, Haase A, Matthaei D (1986) Rapid three-dimensional MR imaging using the FLASH technique. J Comput Assist Tomogr 10:363–368

    Google Scholar 

  4. Runge VM, Wood ML, Kaufmann DM, Nelson KL, Traill MR (1988) FLASH: clinical three-dimensional magnetic resonance imaging. RadioGraphics 8: 947–965

    Google Scholar 

  5. Haase A, Matthaei D, Bartkowski R, Dühmke E, Leibfritz D (1989) Inversion recovery snapshot FLASH MR imaging. J Comput Assist Tomogr 13: 1036–1040

    Google Scholar 

  6. Mugler JP, Brookeman JR (1990) Three-dimensional magnetization-prepared rapid gradient-echo imaging (3D MP RAGE). Magn Reson Med 15:152–157

    Google Scholar 

  7. Runge VM, Kirsch JE, Thomas GS, Mugler JP III (1991) Clinical comparison of three-dimensional MP-RAGE and FLASH techniques for MR imaging of the head. J Magn Reson Imaging 1:493–500

    Google Scholar 

  8. Brant-Zawadzki M, Gillan GD, Nitz WR (1992) MP RAGE: a three-dimensional, T1-weighted gradient-echo sequence—initial experience in the brain. Radiology 182:769–775

    Google Scholar 

  9. Mugler JP III, Brookeman JR (1991) Rapid three-dimensional T1-weighted MR imaging with the MP-RAGE sequence. J Magn Reson Imaging 1:561–567

    Google Scholar 

  10. Constable RT, Gore JC (1992) The loss of small objects in variable TE imaging: implications for FSE, RARE, and EPI. Magn Reson Med 28:9–24

    Google Scholar 

  11. Fellner F, Trenkler J, Schmitt R, Fellner C, Helmberger T, Obletter N, Böhm-Jurkovic H (1994) True proton density and T2 weighted Turbo spin echo sequences for routine MR imaging of the brain. Neuroradiology 36:591–597

    Google Scholar 

  12. Höhne KH, De LaPaz RL, Bernstein R, Taylor C (1987) Combined surface display and reformatting for the three-dimensional analysis of tomographic data. Invest Radiol 22:658–664

    Google Scholar 

  13. Cline HE, Lorensen WE, Kikinis R, Jolesz F (1990) Three-dimensional segmentation of MR images of the head using probability and connectivity. J Comput Assist Tomogr 14:1037–1045

    Google Scholar 

  14. Höhne KH, Hanson WA (1992) Interactive 3D segmentation of MRI and CT volumes using morphological operations. J Comput Assist Tomogr 16:285–294

    Google Scholar 

  15. Brant-Zawadzki MN, Gillan GD, Atkinson DJ, Edalatpour N, Jensen M (1993) Three-dimensional MR imaging and display of intracranial disease: improvements with the MP-RAGE sequence and gadolinium. J Magn Reson Imaging 3:656–662

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Neuroradiology, Oberösterreichische Landesnervenkhuik, Linz, Austria

    F. Feliner & H. Böhm-Jurkovic

  2. Department of Radiodiagnostics, Khelkum Ingolstadt, Ingolstadt, Germany

    F. Feliner & R. Schmitt

  3. Department of Neurosurgery, Oberösterreichische Landesnervenklinik, Linz, Austria

    K. Holl & C. Fellner

  4. Department of Radiology, University of Regensburg, Regensburg, Germany

    P. Held

Authors
  1. F. Feliner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. Holl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. P. Held
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. C. Fellner
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. R. Schmitt
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. H. Böhm-Jurkovic
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Feliner, F., Holl, K., Held, P. et al. A T1-weighted rapid three-dimensional gradient-echo technique (MP-RAGE) in preoperative MRI of intracranial tumours. Neuroradiology 38, 199–206 (1996). https://doi.org/10.1007/BF00596528

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00596528

Key words

Search

Navigation