Abstract
We report recurrent basal cell carcinoma of the scalp with deep cerebral invasion in an 82-year-old man. Plain films and CT showed extensive, full thickness, skull destruction at the vertex. Gadolinium-enhanced MRI revealed neoplastic invasion of the meninges and left cerebral hemisphere, down to the lateral ventricle. We postulate that tumour extended into the brain along perivascular spaces of transcerebral vessels. This hypothesis is supported by the cleft-like contrast enhancement on MRI.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Sober AJ (1983) Diagnosis and management of skin cancer. Cancer 51: 2448–2452
Ko CB, Walton S, Keczkes K (1992) Extensive and fatal basal cell carcinoma: a report of three cases. Br J Dermatol 127:164–167
Habif TP (1990) Clinical dermatology: a color guide to diagnosis and therapy, 2nd edn. Mosby, St. Louis, pp 519–528
Jacobs GH, Rippey JJ, Altini M (1982) Prediction of aggressive behavior in basal cell carcinoma. Cancer 49:533–537
Braun-Falco O, Plewig G, Wolff HH, Winkelmann RK (1991) Dermatology. Springer, Berlin Heidelberg New York, pp 1018–1035
Carter DM (1987) Basal cell carcinoma. In: Fitzpatrick TB, Eisen AZ, Wolff K, Freedberg IM, Austen KF (eds). Dermatology in general medicine: textbook and atlas, 3rd edn. McGraw-Hill, New York, pp 759–765
Rook A, Wilkinson DS, Ebling FJG, Champion RH, Burton JL (1986) Textbook of dermatology, vol 1, 4th edn. Blackwell, Oxford, pp 2417–2424
Long SD, Kuhn MJ, Wynstra JH (1993) Intracranial extension of basal cell carcinoma of the scalp. Comput Med Imaging Graph 17:469–471
Gussack GS, Schlitt M, Lushington A, Woods KE (1989) Invasive basal cell carcinoma of the temporal bone. Ear Nose Throat J 68:605–611
Rubinstein LJ (1972) Tumors of the central nervous system, 2nd series. Armed Forces Institute of Pathology, Washington, DC
Proper SA, Rose PT, Fenske NA (1990) Non-melanomatous skin cancer in the elderly: diagnosis and management. Geriatrics 45:57–62
Mikhail GR, Boulos RS, Knighton RS (1986) Cranial invasion by basal cell carcinoma. J Dermatol Surg Oncol 12: 459–464
Nelson MD, González-Gómez I, Gilles FH (1991) The search for human telencephalic ventriculofugal arteries. AJNR 12:215–222
Vander Eecken HM, Adams RD (1953) The anatomy and functional significance of the meningeal arterial anastomoses of the human brain. J Neuropathol Exp Neurol 12:132–157
DeReuck J (1971) The human periventricular arterial blood supply and the anatomy of cerebral infarctions. Eur Neurol 5:321–334
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Parizel, P.M., Dirix, L., Van den Weyngaert, D. et al. Deep cerebral invasion by basal cell carcinoma of the scalp. Neuroradiology 38, 575–577 (1996). https://doi.org/10.1007/BF00626103
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00626103