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Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

We describe a patient with AIDS who presented with focal neurological symptoms, and who had contrast-enhancing brain lesions on MRI which demonstrated increased thallium-201 uptake on SPECT. These findings were consistent with lymphoma; however, brain biopsy established a diagnosis of progressive multifocal leukoencephalopathy (PML). To our knowledge, this is the first reported case of PML with increased thallium-201 uptake on brain SPECT.

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Authors and Affiliations

  1. Russell H. Morgan Department of Radiology, Johns Hopkins Medical School, 600 N. Wolfe St. Baltimore, MD 21287, USA, , , , , , TP

    J. D. Port, S. Miseljic, R. R. Lee & B. B. Chin

  2. Department of Pathology, Johns Hopkins Medical School, 600 N. Wolfe St. Baltimore, MD 21287, USA, , , , , , TP

    S. Z. Ali & T. L. Nicol

  3. Department of Neurology Johns Hopkins Medical School, 600 N. Wolfe St. Baltimore, MD 21287, USA, , , , , , TP

    W. Royal III

Authors
  1. J. D. Port
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  2. S. Miseljic
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  3. R. R. Lee
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  4. S. Z. Ali
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  5. T. L. Nicol
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  6. W. Royal III
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  7. B. B. Chin
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Received: 9 September 1998 Accepted: 25 March 1999

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Port, J., Miseljic, S., Lee, R. et al. Progressive multifocal leukoencephalopathy demonstrating contrast enhancement on MRI and uptake of thallium-201: a case report. Neuroradiology 41, 895–898 (1999). https://doi.org/10.1007/s002340050862

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  • DOI: https://doi.org/10.1007/s002340050862

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