Abstract
We report two toddlers with portosystemic shunts who had symmetrical high-signal globus pallidus lesions on T1- but not T2-weighted MRI, and measurement of whole blood manganese at 2 years of age. These cases suggest that portosystemic shunts can cause elevation of blood manganese and result in manganese accumulation in the globus pallidus, causing high signal on T1-weighted images even in asymptomatic toddlers.
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Received: 13 April 1998 Accepted: 23 July 1998
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Ihara, K., Hijii, T., Kuromaru, R. et al. High-intensity basal ganglia lesions on T1-weighted images in two toddlers with elevated blood manganese with portosystemic shunts. Neuroradiology 41, 195–198 (1999). https://doi.org/10.1007/s002340050733
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DOI: https://doi.org/10.1007/s002340050733