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Focal cortical dysplasia of the temporal lobe with late-onset partial epilepsy: serial quantitative MRI

  • DIAGNOSTIC NEURORADIOLOGY
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Abstract

We describe serial studies of focal cortical dysplasia causing temporal lobe seizures and progressive aphasia in a 54-year-old woman. Initially, MRI volumetry of the temporal lobes showed significant left cortical thickening corresponding to an elevated aminoacid uptake in the left temporoparietal and inferior frontal cortex on SPECT using 3-[123I]iodo-α-methyl-l-tyrosine (IMT). After 1 year there was severe shrinkage of the left temporal lobe, possibly the result of recurrent complex partial seizures.

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Authors and Affiliations

  1. Department of Neurology, Heinrich-Heine University, Moorenstraße 5, 40225 Düsseldorf Tel.: +49-2 11-8 11 63 22 Fax: 49-2 11-8 11 845, , , , , , DE

    J. Rademacher & R. J. Seitz

  2. Department of Radiology, Heinrich-Heine University, Düsseldorf, Germany, , , , , , DE

    A. Aulich

  3. Department of Neuropathology, Heinrich-Heine University, Düsseldorf, Germany, , , , , , DE

    G. Reifenberger

  4. Department of Neurosurgery, Heinrich-Heine University, Düsseldorf, Germany, , , , , , DE

    J. C. W. Kiwit

  5. Institute of Medicine, Research Center Jülich, Heinrich-Heine University, Düsseldorf, Germany, , , , , , DE

    K. J. Langen & D. Schmidt

Authors
  1. J. Rademacher
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  2. A. Aulich
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  3. G. Reifenberger
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  4. J. C. W. Kiwit
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  5. K. J. Langen
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  6. D. Schmidt
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  7. R. J. Seitz
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Additional information

Received: 16 July 1999/Accepted: 20 September 1999

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Rademacher, J., Aulich, A., Reifenberger, G. et al. Focal cortical dysplasia of the temporal lobe with late-onset partial epilepsy: serial quantitative MRI. Neuroradiology 42, 430–435 (2000). https://doi.org/10.1007/s002340000304

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  • DOI: https://doi.org/10.1007/s002340000304

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