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The effect of oestrogen on stromal growth of the dog prostate: A quantitative ultrastructural study

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Summary

The stromal tissue of the prostate in normal castrated dogs and castrated and oestrogen treated dogs were studied by quantitative morphological methods. Quantitative morphological (=stereological) procedures provide values of volume, surface and number of tissue and cell components. The stereological data show an activation of the smooth muscle cell of the stromal tissue in the oestrogen treated dog compared with the control group; related to the unit volume of smooth muscle cell cytoplasm, a threefold increase of the endoplasmic reticulum was observed in castrated and oestrogen treated dogs.

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Abbreviations

SMC:

Smooth muscle cell

N:

Nucleus

EX:

Extracellular space

CYT:

Cytoplasm

MF:

Myofilaments

R:

Ribosomes

ER:

Endoplasmic reticulum

G:

Golgi apparatus

M:

Mitochondria

VAC:

Vacuoles

VES:

Vesicles

LY:

Lysosomes

VV :

Volume density

COMP:

Cellular compartments

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Authors and Affiliations

  1. Department of Pathology, University of Basel, Basel, Switzerland

    H. P. Rohr, H. R. Naef, O. Holliger & M. Oberholzer

  2. Department of Urology, University of Innsbruck, Innsbruck, Austria

    G. Bartsch

  3. Department of Urology, University of Bonn, Bonn, Federal Republic of Germany

    B. Ibach & L. Weissbach

Authors
  1. H. P. Rohr
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  2. H. R. Naef
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  3. O. Holliger
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  4. M. Oberholzer
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  5. B. Ibach
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  6. L. Weissbach
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  7. G. Bartsch
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Additional information

Supported by the Swiss National Science Foundation, (3.286-0.78) Switzerland and by the Fonds zur Förderung der wissenschaftlichen Forschung (3278 and 4030), Austria

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Rohr, H.P., Naef, H.R., Holliger, O. et al. The effect of oestrogen on stromal growth of the dog prostate: A quantitative ultrastructural study. Urol. Res. 9, 201–207 (1981). https://doi.org/10.1007/BF00264827

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  • DOI: https://doi.org/10.1007/BF00264827

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