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Cortical heterotopia in Aicardi's syndrome — CT findings

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Abstract

A case of 5-month-old female infant with Aicardi's syndrome is presented. The main clinical features were severe developmental retardation and intractable epileptic seizures. Ophthalmoscopic examination revealed pathognomonic chorioretinopathy. Ultrasonic examination of the brain detected agenesis of the corpus callosum, whereas CT showed a coexisting malformation of the brain, i.e. cortical heterotopia of the gray matter. Agenesis of the corpus callosum is an entity well-recognized by sonography. However ultrasonography is an insufficient modality for the visualization of cortical heterotopia which is common to all cases of Aicardi's syndrome. Therefore, in cases of suspected Aicardi's syndrome CT is recommended, as it enables the diagnosis of cortical heterotopia.

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Authors and Affiliations

  1. Department of Paediatrics, Institute of Radiology, Medical School and Institute of Child Health, Zagreb, Yugoslavia

    N. Bešenski, V. Bošnjak, I. Ligutić & B. Marušié-Della Marina

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  1. N. Bešenski
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  2. V. Bošnjak
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  3. I. Ligutić
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  4. B. Marušié-Della Marina
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Bešenski, N., Bošnjak, V., Ligutić, I. et al. Cortical heterotopia in Aicardi's syndrome — CT findings. Pediatr Radiol 18, 391–393 (1988). https://doi.org/10.1007/BF02388043

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  • DOI: https://doi.org/10.1007/BF02388043

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