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Effects of an inhomogeneous magnetic field on flowing erythrocytes

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Abstract

Effects of an inhomogeneous magnetic field on narrow erythrocyte streams in a wide and transparent laminar buffer flow were studied. The stream line of erythrocytes containing paramagnetic hemoglobin showed distinct displacement toward the stronger magnetic field. The displacement increased in the order, oxygenated erythrocytes (no displacement), erythrocytes containing cyanomethemoglobin, deoxygenated erythrocytes, erythrocytes containing methemoglobin in the high spin state; more precisely the displacement was proportional to the square of the paramagnetic moment of hemoglobin contained in the erythrocytes. In addition, the displacement was proportional to the product of the magnetic flux density and its gradient, and approximately proportional to the hematocrit of the flowing-erythrocyte suspension, and was much larger than that calculated for a single erythrocyte. These phenomena could be successfully interpreted by the interaction of paramagnetic erythrocytes with the inhomogeneous magnetic field, the resistance force (Stokes Law) from the bulk water, and the hydrodynamic interaction between erythrocytes.

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Authors and Affiliations

  1. Department of Physiology, School of Medicine, Ehime University, Shigenobu, Onsen-gun, 791-02, Ehime, Japan

    M. Okazaki, N. Maeda & T. Shiga

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  1. M. Okazaki
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  2. N. Maeda
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  3. T. Shiga
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Okazaki, M., Maeda, N. & Shiga, T. Effects of an inhomogeneous magnetic field on flowing erythrocytes. Eur Biophys J 14, 139–145 (1987). https://doi.org/10.1007/BF00253838

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  • DOI: https://doi.org/10.1007/BF00253838

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