This is a preview of subscription content, log in via an institution to check access.
References
Accolla, R. S., Gross, N., Carrel, S., and Corte, G.: Distinct forms of both α and β subunits are present in the human Ia molecular pool. Proc. Natl. Acad. Sci. U.S.A. 78: 4549–4551, 1981
Bono, M. R. and Strominger, J. L.: Direct evidence of homology between human DC-1 antigens and murine I-A molecules. Nature 299: 836–838, 1982
Charron, D. J. and McDevitt, H. O.: Characterization of HLA-D-region antigens by two-dimensional gel electrophoresis. Molecular genotyping. J. Exp. Med. 152: 18s-36s, 1980
DeKretser, T. A., Crumpton, M. J., Bodmer, J. G., and Bodmer, W. F.: Demonstration of two distinct light chains in HLA-DR-associated antigens by two-dimensional gel electrophoresis. Eur. J. Immunol. 12: 214–221, 1982
Groner, J. P., Watson, A. J., and Bach, F. H.: Dw/LD-related molecular polymorphism of DR4 β-chains. J. Exp. Med. 157: 1687–1691, 1983
Hurley, K. C., Nunez, G., Winchester, R., Finn, O. J., Levy, R., and Capra, J. D.: The human HLA-DR antigens are encoded by multiple chain loci. J. Immunol. 129: 2103–2108, 1982
Igarashi, M., Yoshii, M., and Kashiwagi, N.: Biochemical heterogeneity of human Ia-like antigens analyzed by monoclonal antibodies. Transplant. Proc. 1: 84–88, 1983
Ivanyi, P., Gyodi, E., Gyorffy, G. Y., Pavlyjukova, H., Ivaskova, E., and Petanyi, G. Y.: Cytotoxic effect of anti-H-2 and anti-Ia antisera on human B and T cells. Scand. J. Immunol. 6: 432–437, 1977
Kratzin, H., Yang, C.-Y., Gotz, H., Pauly, E., Kolbel, S., Egert, G., Thinnes, F. P., Werner, P., Altevogt, P., and Hilschmann, N.: Primärstruktur menschlicher Histokompatibilitätsantigene der Klasse II. Hoppe Seylers Z. Physiol. Chem. 363: 1655–1699, 1981
Lampson, L. A. and Levy, R.: Two populations of Ia-like molecules on a human B cell line. J. Immunol. 125: 293–299, 1980
Machamer, C. E. and Cresswell, P.: Biosynthesis and glycosylation of the invariant chain associated with HLA-DR antigens. J. Immunol. 129: 2564–2569, 1982
Nadler, L. M., Stashenko, P., Hardy, R., Pesando, J. M., Yunis, E. J., and Schlossman, S. F.: Monoclonal antibodies defining serologically distinct HLA-D/DR related la-like antigens in man. Hum. Immunol. 1: 77–90, 1981
Pellegrino, M. A., Ferrone, S., Mittal, K. K., Gotze, D., Terasaki, P. I., and Reisfeld, R. A.: Cross-reactivity between human and murine lymphocyte antigens. III. Reactivity of H-2 allo- and xenoantisera with human lymphoid cells. Immunogenetics 1: 158–173, 1974
Pierres, M., Rebouah, J. P., Kourilsky, F. M., Dosseto, M., Mercier, P., Mawas, C., and Malissen, B.: Cross-reactions between mouse Ia and human HLA-D/DR antigens analyzed with monoclonal allo-antibodies. J. Immunol. 126: 2424–2429, 1981
Quaranta, V., Pellegrino, M. A., and Ferrone, S.: Serological and immunochemical characterization of the specificity of four monoclonal antibodies to distinct antigenic determinants expressed on subpopulation of human Ia-like antigens. J. Immunol. 126: 548–552, 1981a
Quaranta, V., Pellegrino, M. A., and Ferrone, S.: The monoclonal xenoantibody Q6/64 recognizes a determinant shared by certain gene products of the A and B loci of the the HLA region. Immunogenetics 14: 403–413, 1981b
Schackelford, D. A. and Strominger, J. L.: Demonstration of structural polymorphism among HLA-DR light chains by two-dimensional gel electrophoresis. J. Exp. Med. 151: 144–165, 1980
Shinohara, N., Sachs, D. H., Nonaka, N., and Yamamoto, H.: Phylogenetic tracing of Ia genes. Nature 292: 362–363, 1981
Silver, J. and Ferrone, S.: Structural polymorphism of human DR antigens. Nature 279: 436–439, 1979
Silver, J., Walker, L. E., Reisfeld, R. A., Pellegrino, M. A., and Ferrone, S.: Structural studies of murine I-E and human DR antigens. Mol. Immunol. 16: 37–42, 1979
Steinmetz, M., Minard, K., Horvath, S., McNicholas, J., Strelinger, J., Wake, C., Long, E., Mach, B., and Hood, L.: A molecular map of the immune response region from the major histocompatibility complex of the mouse. Nature 300: 35–42, 1982
Tosi, R., Tanigaki, N., Sorrentino, R., van Mourik, P., and Ivanyi, P.: Human Ia molecules carrying DC1 or BR4x7 determinants are not homologous to murine I-E molecules. Immunogenetics 16: 187–199, 1982
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Igarashi, M., Obata, F., Yoshii, M. et al. Structural polymorphism of human Ia antigens recognized by the monoclonal antibody 12 and by cross-reacting I-Ek-specific alloantibodies. Immunogenetics 19, 249–255 (1984). https://doi.org/10.1007/BF00364768
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00364768