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Metabolism of the polycyclic aromatic hydrocarbon pyrene by Aspergillus niger SK 9317

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Abstract

The metabolism of pyrene, a polycyclic aromatic hydrocarbon consisting of four rings, by Aspergillus niger SK 9317 was investigated. The metabolites formed were isolated and identified as 1-hydroxypyrene, 1,6- and 1,8-pyrenequinone, 1,6- and 1,8-dihydroxypyrene, 1-pyrenyl sulphate and 1-hydroxy-8-pyrenyl sulphate. This is the first report of 1-hydroxy-8-pyrenyl as a metabolite in the microbial metabolism of pyrene. The results suggest that A. niger metabolizes pyrene by cytochrome P-450 monooxygenase enzyme systems.

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Authors and Affiliations

  1. Department of Biotechnology, University of Kaiserslautern, Paul-Ehrlich-Strasse 23, D-67663, Kaiserslautern, Germany

    T. Wunder, S. Kremer & H. Anke

  2. Department of Organic Chemistry 2, Chemical Center, University of Lund, P.O. Box 124, S-211 00, Lund, Sweden

    O. Sterner

Authors
  1. T. Wunder
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  2. S. Kremer
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  3. O. Sterner
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  4. H. Anke
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Wunder, T., Kremer, S., Sterner, O. et al. Metabolism of the polycyclic aromatic hydrocarbon pyrene by Aspergillus niger SK 9317. Appl Microbiol Biotechnol 42, 636–641 (1994). https://doi.org/10.1007/BF00173932

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  • DOI: https://doi.org/10.1007/BF00173932

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