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Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component

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Skeletal Radiology Aims and scope Submit manuscript

Abstract 

We report a case of chordoma containing a spindle cell sarcomatoid component with a gradual transition from conventional chordoma. Immunohistochemically, many tumor cells in both conventional chordoma and sarcomatoid components were positive for cytokeratins (AE1/AE3, CAM5.2) and epithelial membrane antigen as well as vimentin. This report provides a rare example of sarcomatoid chordoma. Familiarity with this type of bone tumor should help to avoid confusion with dedifferentiated chordoma and other spindle cell sarcomas or carcinomas.

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Authors and Affiliations

  1. Department of Pathology and Oncology, School of Medicine, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu-shi 807-8555, Japan, , , , , , JP

    Yosuke Morimitsu & H. Hashimoto

  2. Department of Radiology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, , , , , , JP

    Takatoshi Aoki

  3. Department of Orthopedics, National Kokura Hospital, Kitakyushu, Japan, , , , , , JP

    Koichiro Yokoyama

Authors
  1. Yosuke Morimitsu
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  2. Takatoshi Aoki
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  3. Koichiro Yokoyama
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  4. H. Hashimoto
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Additional information

Received: 25 February 2000 Revision requested: 28 March 2000 Revision received: 30 May 2000 Accepted: 28 June 2000

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Morimitsu, Y., Aoki, T., Yokoyama, K. et al. Sarcomatoid chordoma: chordoma with a massive malignant spindle-cell component. Skeletal Radiol 29, 721–725 (2000). https://doi.org/10.1007/s002560000264

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  • DOI: https://doi.org/10.1007/s002560000264

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