Abstract
Eighteen patients were examined at rest by technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) myocardial scintigraphy 1 day before and 1 week after aorto-coronary bypass operation with planar and single photon emission tomography (SPET) imaging. One day postoperatively, a planar scintigraph in the intensive care unit (ICU) was done. Inter-observer variability was 3.8% for all examinations and for SPET alone, 3.9%. The quality of the planar images taken under emergency conditions in the ICU was quite comparable with those taken under routine conditions. The postoperative myocardial infarction in a patient who died 6 days later could clearly be demonstrated. In 16.2% of all segments which were hypoperfused at rest on preoperative scintigraphy, an amelioration of perfusion could be shown in the 1 st week after the bypass operation.99Tc-MIBI proved to be a useful agent to assess perioperative perfusion, in the ICU as well as under standard conditions.
Similar content being viewed by others
References
Faraggi M, Messian O, Assayag P, Thonnart B, Brochet E, Valère P, Bok B (1989) Assessment of response to reperfusion after thrombolysis in acute myocardial infarction (AMI): usefulness of MIBI SPECT. Eur J Nucl Med 15:399 (abstract 2)
Kiat H, Maddahi J, Roy LT (1989) Comparison of technetium 99m methoxy isobutyl isonitrile and thallium 201 for evaluation of coronary artery disease by planar and tomographic methods. Am Heart J 117:1, 1–11
Larock MP, Cantineau R, Rigo P (1988) Tc-MIBI to define the extent of myocardial ischemia and evaluate ventricular function. Eur J Nucl Med 14:240 (abstract 108)
Maddahi J, Merz R, Van Train KF (1987) Tc 99m MIBI (RP 30) and TI-201 myocardial perfusion scintigraphy in patients with coronary disease: quantitative comparison of planar and tomographic techniques for perfusion defect intensity and defect reversibility. J Nucl Med 28:654 (abstract)
Mayer JC, Karcher G, Matbiev E, Maublant J, Itti R, Bourguignon M, Moretti JL, Baconnet B, Bertrand A (1988) Comparative study by two independent observers of the uptake abnormalities of 201 thallium and Tc 99m-MIBI in 81 patients with coronary artery disease. Eur J Nucl Med 14:248 (abstract 152)
Okada RD, Glover D, Graffney T, Williams S (1988) Myocardial kinetics of technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile. Circulation 77 (2):491–498
Sciagrà R, Bisi G, De Cristofaro MTR, Santoro GM, Pupi A (1988) Superiority of99mTc-MIBI over201TI for SPECT evaluation of coronary artery disease. Eur J Nucl Med 14:248 (abstract 155)
Stone DL, Weiss AT, Snyder SH, Yaffe S, Gotsman MS, Atlan H (1989) A comparison of planar and tomographic thallium scintigraphy in patients with coronary artery disease. Eur J Nucl Med 15:244–247
Tillich J, Brunken R, Marshall R (1986) Reversibility of c/ardiac wall-motion abnormalities predicted by positron tomography. N Engl J Med 314:884–888
Watson DD, Smith WH, Teates CD, Beller GA (1987) Quantitative myocardial imaging with Tc-99m MIBI: comparison with TI-201. J Nucl Med 28:653 (abstract)
Author information
Authors and Affiliations
Additional information
Offprint requests to: G.K. von Schulthess
Rights and permissions
About this article
Cite this article
Raff, W., Sialer, G., von Segesser, L. et al. Perioperative myocardial perfusion scintigraphy at rest with technetium 99m methoxyisobutylisonitrile before and after coronary bypass operations. Eur J Nucl Med 18, 99–105 (1991). https://doi.org/10.1007/BF00950754
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00950754