Summary
Thirty-seven femoral heads in idiopathic avascular necrosis of adults and fifty-seven biopsy specimens of the capital nucleus of Perthes' disease were studied histologically. Although the early pathological changes in these two diseases are very similar, in the intermediate and late (advanced) stages they gradually take differing courses. Although the initiating causes in both diseases are still obscure both are probably produced by repeated episodes of infarction of the femoral head.
Résumé
Les auteurs ont pratiqué l'étude histologique de 37 têtes fémorales atteintes de nécrose avasculaire idiopathique de l'adulte et de 57 biopsies du noyau de la tête fémorale dans la maladie de Legg-Perthes-Calvé. Bien que les modifications pathologiques précoces soient semblables dans ces deux maladies, elles divergent aux stades intermédiaire et terminal. Si la cause déterminante de ces maladies reste obscure, les deux sont vraisemblablement produites par des épisodes répétés d'infarcissement de la tête fémorale.
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References
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Inoue, A., Ono, K., Takaoka, K. et al. A comparative study of histology in perthes' disease and idiopathic avascular necrosis of the femoral head in adults (IANF). International Orthopaedics 4, 39–46 (1980). https://doi.org/10.1007/BF00266602
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DOI: https://doi.org/10.1007/BF00266602