Summary
Among 55 amyloidoses, the detection of a monoclonal protein (MP) led to the selection of 15 primary and 3 myeloma-associated types of amyloidosis. Therefore the presence of a MP gives evidence for an immunocytic amyloidosis.
The λ-light-chain nature of MP and the abundant production of free light-chains are two of the factors predisposing to the production of amyloid deposits (AL) in the course of immunocyte dyscrasias.
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Durand, D.V., Touraine, JL., Levrat, R. et al. Immunoelectrophoretic investigations in 55 patients with systemic amyloidosis. Blut 49, 91–94 (1984). https://doi.org/10.1007/BF00363699
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DOI: https://doi.org/10.1007/BF00363699