Abstract
Based on the four compartment model by Grodins we develop a model for the response of the cardiovascular system to a short term submaximal workload. Basic mechanisms included in the model are Starling's law of the heart, the Bowditch effect and autoregulation in the peripheral regions. A fundamental assumption is that the action of the feedback control is represented by the baroceptor loop and minimizes a quadratic cost functional. Simulation results show that the model provides a satisfactory description of data obtained in bicycle ergometer tests.
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Kappel, F., Peer, R.O. A mathematical model for fundamental regulation processes in the cardiovascular system. J. Math. Biol. 31, 611–631 (1993). https://doi.org/10.1007/BF00161201
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DOI: https://doi.org/10.1007/BF00161201