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Sonographic diagnosis of solitary solid liver nodules in cancer patients

  • Abdominal and Gastrointestinal Radiology
  • Original Article
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Abstract

The purpose of this study was to analyse the sonographic patterns of solitary solid liver lesions in cancer patients and to evaluate the diagnostic accuracy of ultrasound alone and in combination with other techniques (liver function tests, histology). A total of 422 solitary solid liver lesions (SSLL) were diagnosed by ultrasound in cancer patients; 197 lesions were benign and 225 malignant. The predominant aetiology for hypoechoic SSLL (128 cases) was metastasis (112 cases), whereas most hyperechoic SSLL (265 cases) were haemangiomas (155 cases) rather than a metastasis (86 cases). The 29 isoechoic SSLL included 27 metastases and 2 benign lesions. A halo was found to be highly predictive of malignancy (97%–100%). The positive predictive value for malignancy of an SSLL was very high when the results of liver function tests were abnormal (97%–100%). In our experience, histological proof is unnecessary in the majority of liver lesions in cancer patients.

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References

  1. Vitale GC, Heuser LS, Polk HC Jr (1986) Malignant tumors of the liver. Surg Clin North Am 66: 723

    Google Scholar 

  2. Ismak KG, Rabin L (1975) Benign tumors of the liver. Med Clin North Am 59: 995

    CAS  PubMed  Google Scholar 

  3. Bruneton JN (1993) Imagerie des tumeurs du foie. Masson, Paris

    Google Scholar 

  4. Karhunen PJ (1986). Benign hepatic tumours and tumour like conditions in men. J Clin Pathol 39: 183

    Google Scholar 

  5. Machi J, Isomoto H, Yamashita Y, et al (1987) Intraoperative ultrasonography in screening for liver metastases from colorectal cancer: comparative study accuracy with traditional procedures. Surgery 101: 678

    Google Scholar 

  6. Schreve RH, Terpstra DT, Ausema L, et al (1984) Detection of liver metastases: a prospective study comparing liver enzymes, scintigraphy, ultrasonography and computed tomography. Br J Surg 71: 947

    Google Scholar 

  7. Wernecke K, Vassallo P, Bick U, Diederich S, Peter PE (1992) The distinction between benign and malignant tumors on sonography: value of a hypoechoic halo. AJR 159: 1005

    Google Scholar 

  8. Rosenbuch G, Smits NJ, Reeders JMAJ (1989) Ultrasonography in hepatobiliary and pancreatic malignancies. In Lygidakis NJ, Tytgat GNJ (eds) Hepatobiliary and pancreatic malignancies: diagnosis, medical and surgical management. Thieme, Stuttgart, pp 51–65

    Google Scholar 

  9. Tanaka S, Kitamura T, Imaoka S, et al (1983) Hepatocellular carcinoma: sonographic and histologic correlation. AJR 140: 701

    Google Scholar 

  10. Tempero MA, Williams CA, Anderson JC (1986) The value of hepatic ultrasound and biochemical limit tests in screening for liver metastases. J Clin Biol 4: 1074

    Google Scholar 

  11. Adloff M, Arnaud JP (1985) Etude prospective critique des différentes méthodes de détection des métastases hépatiques. Ann Gastroenterol Hepatol 21: 31

    Google Scholar 

  12. Rafaelsen SR, Kronbor O, Larsen C, Fenger C (1995) Intraoperative ultrasonography in detection of hepatic metastases from colorectal cancer. Dis Colon Rectum 38: 355

    Google Scholar 

  13. Khattar SC, Torjo-Pedersen ST, Lorentsen T, et al (1994) Liver metastases: is biopsy verification necessary when sonographic assessment is certain? Eur J Ultrasound 1: 67

    Google Scholar 

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Correspondence to: J. N. Bruneton

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Bruneton, JN., Raffaelli, C., Balu-Maestro, C. et al. Sonographic diagnosis of solitary solid liver nodules in cancer patients. Eur. Radiol. 6, 439–442 (1996). https://doi.org/10.1007/BF00182462

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  • DOI: https://doi.org/10.1007/BF00182462

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