Skip to main content
SpringerLink
Log in

Deficient platelet-activating factor and related enzymes in hemimegalencephaly

  • ORIGINAL PAPER
  • Published:
Child's Nervous System Aims and scope Submit manuscript

Abstract

Platelet-activating factor (PAF) may influence neuronal migration, and gyral anomaly in hemimegalencephaly is believed to result from a neuronal disorder. A 7-month-old girl with hemimegalencephaly presented with intractable seizures, for which graded hemispherectomy was performed. In the resected specimen, we could not detect PAF, and related enzyme activities were low. These results suggest a role of PAF in neuronal migration.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama-shi, Toyama 930-0194, Japan e-mail: yhira@ms.toyama-mpu.ac.jp Tel.: +81-764-34-2281 Fax: +81-764-34-5034, , , , , , JP

    Y. Hirashima, Shunro Endo, Masanori Kurimoto, Hiroaki Ikeda & Akira Takaku

  2. Faculty of Pharmaceutical Sciences, Teikyo University, Sunzawaarashi 1901-1, Sagamiko-cho, Tsukui-gun, Kanagawa 199-01, Japan, , , , , , JP

    Kenn Karasawa, Noriko Sato, Kazuaki Yokoyama & Morio Setaka

Authors
  1. Y. Hirashima
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Shunro Endo
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kenn Karasawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Noriko Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kazuaki Yokoyama
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Masanori Kurimoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Hiroaki Ikeda
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Morio Setaka
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Akira Takaku
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 23 February 1998 Revised: 26 June 1998

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hirashima, Y., Endo, S., Karasawa, K. et al. Deficient platelet-activating factor and related enzymes in hemimegalencephaly. Child's Nerv Syst 15, 98–101 (1999). https://doi.org/10.1007/s003810050341

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s003810050341

Search

Navigation