Abstract
Children with chronic respiratory diseases may be a high-risk population for gastroesophageal reflux (GER). In order to describe GER in this population, we systematically studied 7-h pH-metry and prolonged esophageal manometry (over 45 min) in 124 children admitted for respiratory disorders without digestive symptoms. The results showed that: (1) GER varied in significance before and after meals; (2) postprandial reflux was correlated with esophageal motor activity, but preprandial reflux was not; (3) moderate refluxers had reduced lower esophageal sphincter (LES) pressure, but severe refluxers had no significative decrease in LES pressure. The use of multivariate analysis permitted us to conclude that long-term esophageal manometry and pH-metry were complementary in defining severe GER.
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Bouchoucha, M., Arhan, P., de Blic, J. et al. Esophageal motility and gastroesophageal reflux in children with chronic respiratory diseases. Pediatr Surg Int 3, 400–406 (1988). https://doi.org/10.1007/BF00173454
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DOI: https://doi.org/10.1007/BF00173454