Summary
Histochemical studies of type II myoclonus bodies demonstrated that they were composed of a saccharide-lipid complex with a small amount of protein. In particular, they contained phospholipid, ganglioside and sphingomyelin.
The ultrastructure of the bodies revealed that they were bound by a membrane. They were diffusely stippled or homogeneous. They were not formed of filaments or lamellae. Some correlation with microbody or lysosomal structures in association with degeneration of the neurone was suggested.
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Ota, T., Hisatomi, Y., Kashiwamura, K. et al. Histochemistry and ultrastructure of atypical myoclonus body (type II). Acta Neuropathol 28, 45–54 (1974). https://doi.org/10.1007/BF00687517
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DOI: https://doi.org/10.1007/BF00687517