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Histochemical study of the oxidative activity in tumors of the nervous system

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Summary

The present research has pointed out some histochemical aspects of the oxidative metabolism of the various types of cells present in tumors of the nervous system.

The variations in the reactions we observed were examined from the following points of view:

  1. a)

    Description of histochemical reactions in the various oncotypes.

  2. b)

    Variations in relation to the stage of differentiation of cellular elements, the evolution of which follows embryogenetic lines.

  3. c)

    Variations in relation to arrangements showing rapid growth with numerous and atypical mitoses and a deficient maturation of the cell.

  4. d)

    Variations in relation to reactive or regressive processes.

Zusammenfassung

Die vorliegende Arbeit behandelt das histochemische Verhalten der Dehydrogenasen verschiedener Zelltypen in Tumoren des Nervensystems.

Die von uns beobachteten Unterschiede in den Reaktionsergebnissen wurden nach den folgenden Gesichtspunkten untersucht:

  1. a)

    Beschreibung der histochemischen Reaktionen in den verschiedenen Tumortypen.

  2. b)

    Reaktionsunterschiede im Zusammenhang mit dem Differenzierungsgrad der Zellelemente, der embryonalen Grundlinien folgt.

  3. c)

    Reaktionsunterschiede in Abhängigkeit von Proliferationszonen mit zahlreichen atypischen Mitosen und ungenügender Zellreife.

  4. d)

    Unterschiede im Zusammenhang mit reaktiven oder regressiven Vorgängen.

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Authors and Affiliations

  1. Div. of Brain Tumors Research, Neurosurg. Clinic of the Univers. of Genova (Italy), Ospedale S. Maritno (Pad. 20F), Genova, (Italia)

    G. L. Viale & L. G. Andreussi

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  1. G. L. Viale
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  2. L. G. Andreussi
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Viale, G.L., Andreussi, L.G. Histochemical study of the oxidative activity in tumors of the nervous system. Acta Neuropathol 4, 538–558 (1965). https://doi.org/10.1007/BF00688513

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