Summary
Paired twisted filaments (PTF) forming helices are described in tumor cells of three human pine-alomas. Each filament was 8.11±1.55 nm wide. The maximal width of the helix was 16.62±2.62 nm. The periodicity of the constrictions was 26.63±4.49 nm. These characteristics appeared original, suggesting protein, filaments possibly specific of pinealocytes. The similarities and discrepancies between PTF and Alzheimer's paired helical filaments (PHF) are discussed.
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Supported by a grant from FEGEFLUC (Fédération Nationale des Groupements des Entreprises Françaises dans la Lutte contre le Cancer), Marseille, France
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Hassoun, J., Devictor, B., Gambarelli, D. et al. Paired twisted filaments a new ultrastructural marker of human pinealomas?. Acta Neuropathol 65, 163–165 (1984). https://doi.org/10.1007/BF00690471
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DOI: https://doi.org/10.1007/BF00690471