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Congenital cerebellar neuroepithelial tumor with multiple divergent differentiations

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Summary

A case of congenital cerebellar tumor is reported. The tumor is composed of a few incomplete tubular structures analogous to the neural tube, and of neuroblastic, mature ganglionic, astrocytic, ependymal and undetermined neuroepithelial cells. A tentative diagnosis of congenital cerebellar neuroepithelial tumor with multiple divergent differentiations is made: the histogenesis is discussed. From a histogenetic point of view this tumor is given the provisional name of matrix cell tumor.

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References

  • Best PV (1974) Posterior fossa medulloepithelioma. Report of a case. J Neurol Sci 22:511–518

    Google Scholar 

  • Chatty EM, Earle KM (1971) Medulloblastoma. A report of 201 cases with emphasis on the relationship of histologic variants to survival. Cancer 28:977–983

    Google Scholar 

  • Dastur DK, Lalitha VS (1968) Pathological analysis of intracranial space-occupying lesions in 1,000 cases including children. Part 2. Incidence, types, and unusual cases of glioma. J. Neurol Sci 8:143–170

    Google Scholar 

  • Deck JHN (1969) Cerebral medulloepithelioma with maturation into ependymal cells and ganglion cells. J Neuropathol Exp Neurol 28:442–454

    Google Scholar 

  • Fowler M (1968) Embryonic ependymoma arising in a cerebral hemisphere. Cancer 21:1150–1156

    Google Scholar 

  • Fujita S (1958) Medulloepithelioma. Its place in the histogenetic classification on neuroectodermal tumors. Acta Pathol Jpn 8:789–794

    Google Scholar 

  • Fujita S (1963) The matrix cell and cytogenesis in the developing central nervous system. J Comp Neurol 120:37–42

    Google Scholar 

  • Fujita S (1964) Analysis of neuron differentiation in the central nervous system by tritiated thymidine autoradiography. J Comp Neurol 122:311–327

    Google Scholar 

  • Fujita S (1965) An autoradiographic study on the origin and fate of the sub-pial glioblast in the embryonic chick spinal cord. J Comp Neurol 124:51–60

    Google Scholar 

  • Fujita S (1973) Genesis of glioblasts in the human spinal cord as revealed by Feulgen cytophotometry. J Comp Neurol 151:25–34

    Google Scholar 

  • Fujita H, Fujita S (1964) Electron microscopic studies on the differentiation of the ependymal cells and the glioblasts in the spinal cord of domestic fowl. Z Zellforsch 64:262–272

    Google Scholar 

  • Gullotta F, Entzian W (1975) Klinische und morphologische Betrachtungen über das “Medulloepitheliom”. Neurochirurgia (Stuttg) 18:193–199

    Google Scholar 

  • Jellinger K (1972) Cerebral medulloepithelioma. Acta Neuropathol (Berl) 22:95–101

    Google Scholar 

  • Kane W, Aronson SM (1967) Gangliomatous maturation in cerebellar medulloblastoma. Acta Neuropathol (Berl) 9:273–279

    Google Scholar 

  • Karch SB, Urich H (1972) Medulloepithelioma: Definition of an entity. J Neuropathol Exp Neurol 31:27–53

    Google Scholar 

  • Kitamura T, Fujita S (1976) Development of the central nervous system — III. Stage III of cytogenesis: stage of neuroglia differentiation (in Japanese with an abstract in English). No To Shinkei 28:218–224

    Google Scholar 

  • Lolova I, Bojinov S, Ivanova A, Christor I (1972) Cerebral medulloepithelioma. Histological and histochemical study of a case. J Neurol Sci 15:173–182

    Google Scholar 

  • Müller W, Schaefer HE (1974) Beitrag zur morphologischen Onkotypie des Medulloblastoms. Acta Neuropathol (Berl) 30:51–61

    Google Scholar 

  • Pollak A, Friede RL (1977) Fine structure of madulloepithelioma. J Neuropathol Exp Neurol 36:712–725

    Google Scholar 

  • Rubinstein LJ (1972) Tumors of the central nervous system, atlas of tumor pathology, Fascicle 6, Second series. Armed Forces Institute of Pathology, Washington

    Google Scholar 

  • Russell DS, Rubinstein LJ (1977) Pathology of tumours of the nervous system, 4th edn. Arnold, London

    Google Scholar 

  • Scheithauer BW, Rubinstein LJ (1979) Cerebral medulloepithelioma. Report of a case with multiple divergent neuroepithelial differentiation. Childs Brain 5:62–71

    Google Scholar 

  • Treip CS (1957) A congenital medulloepithelioma of the brain. J Path Bact 74:357–363

    Google Scholar 

  • Van Epps RR, Samuelson DR, McCormic WF (1967) Cerebral medulloepithelioma. Case report. J Neurosurg 27:568–573

    Google Scholar 

  • Willis RA (1967) Pathology of tumours, 4th edn. Butterworths, London

    Google Scholar 

  • Yoshimura N, Ikuta F, Oyake Y (1973) On the mixture of ependymoblatic, neuroblastic, and spongiobalstic cells in the own and reported cases of medulloepithelioma (In Japanese with an abstract in English). Adv Neurol Sci (Tokyo) 17:103–116

    Google Scholar 

  • Zimmerman HM (1959) Medulloepithelioma (malignant ependymoma). In: American Society of Clinical Pathologists; Seminar on diseases of nervous tissue and muscle. Proc. 24th Seminar of the American Society of Clinical Pathologists, Chicago, 1958. American Society of Clinical Pathologists, Chicago, Ill

    Google Scholar 

  • Zülch KJ (1971) Atlas of the histology of brain tumors. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Zülch KJ (1975) Atlas of gross neurosurgical pathology. Springer, Berlin Heidelberg New York

    Google Scholar 

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Sato, T., Shimoda, A., Takahashi, T. et al. Congenital cerebellar neuroepithelial tumor with multiple divergent differentiations. Acta Neuropathol 50, 143–146 (1980). https://doi.org/10.1007/BF00692865

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  • DOI: https://doi.org/10.1007/BF00692865

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