Summary
Report of a 33-year-old man with a yearlong historory of low-back pain radiating into the left leg. Neurologic examination upon admission tto the hospital revealed a spinal compression syndrome at the lovel L5. Laminectomy at L4/5 revealed an encapsulated intradural tumor measuring 4×2.5×2.5 cm. The tumor was attached to the dorsal root L4 and extended downward to the conus region. Light and electron microscopy revealed features mostly consistent with a mixed chemodectoma and ganglioneuroma.
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Alphen HAM van, Bellot SM, Stam FC (1977) Paraganglioma of cauda equina. Clin Neurol Neurosurg 79:316–322
Andrew A (1976) APUD cells, apudomas and the neural crest. S Afr Med J 50:890–898
Beltrami CA, Montironi R, Cinti S (1980) Gangliocytic paraganglioma of the duodenum: case report. Tumori 66:637–641
Beltran GE, Leiderman E, Stuckey WJ Jr, Ferrans VJ, Mogabcab WJ (1969) Metastatic ganglioneuroblastoma: ultrastructural, histochemical, and virological studies in a case. Cancer 24:552–559
Bílbao JM, Horvath E, Kovacs K, Singer W, Hudson AR (1978) Intrasellar paraganglioma associated with hypopituitarism. Arch Pathol Lab Med 102:95–98
Burger PC, Vogel FS (1976) Surgical pathology of the nervous system and its coverings. Wiley & Sons, New York London Sydney Toronto
Ciappetta P, Perrino G, Albrizio M (1980) Functionless nonchromaffin retroperitoneal paraganglioma causing cauda equina compression. Acta Neurochir (Wien) 53:181–186
Duncan DK, McDonald JR (1951) Chemodectoma (‘nonchromaffin paraganglioma’). Am J Clin Pathol 21:515–520
Glenner GG, Grimley PM (1974) Tumors of the extra-adrenal paraganglion system (including chemoreceptors). In: AFIP Atlas of tumor pathology, fasc 9. AFIP, Washington, DC
Grimley PM, Glenner GG (1967) Histology and ultrastructure of carotid body paragangliomas. Comparison with the normal gland. Cancer 20:1473–1488
Haber S (1964) Retroperitoneal and mediastinal chemodectoma. Am J Roentgenol 92:1029–1041
Helpap B (1978) Extraadrenale Paraganglien und Paragangliome. In: Bargmann W, Doerr W (Hrsg) Normale und pathologische Anatomie, Bd 37. Thieme, Stuttgart
Hitano A (1978) Some contributions of electron microscopy to the diagnosis of brain tumors. Acta Neuropathol (Berl) 43:119–128
Hirano A (1981) A guide to neuropathology. Igaku Shoin, New York Tokyo
Horoupian DS, Kerson LA, Saiontz H, Valsamis M (1974) Paraganglioma of cauda equina. Clinicopathologic and ultrastructural studies of an unusual case. Cancer 33:1337–1348
Kepes JJ, Zaccharias DL (1971) Gangliocyctic paragangliomas of the duodenum. A report of two cases with light and electron microscopic examination. Cancer 27:61–70
Kohn A (1900) Über den Bau und die Entwicklung der sog. Carotisdrüse. Arch Mikr Anat 56:81–148
Lagacé R, Delage C, Gagné F (1978) Paraganglioma of the filum terminale. Can J Neurol Sci 5:257–260
Lauzon A, Cadotte M (1972) Paragangliome gangliocytaire du duodenum. Un Med Can 101:1584–1586
Lerman RJ, Kaplan ES, Daman L (1972) Ganglioneuroma-paraganglioma of the intradural filum terminale. J Neurosurg 36:652–658
Hena JF, Hirano A, Rubin RC (1979) Paraganglioma in the cauda equina region. Acta Neuropathol (Berl) 46:235–237
Maier HC, Humphreys GE (1958) Intrathoracic pheochromocytoma. J Thorac Surg 87:369–373
Miller CA, Torack RM (1970) Secretory ependymoma of the filum terminale. Acta Neuropathol (Berl) 15:240–250
Pearse AGE (1961) Histochemistry. Theoretical and applied, 2nd edn. Churchill, London
Pearse AGE (1969) The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic and pathologic implications of the concept. J Histochem Cytochem 17:303–313
Reyes MG, Fresco R, Bruetman ME (1977) Mediastinal paraganglioma causing spinal cord compression. J Neurol Neurosurg Psychiatry 40:276–279
Robertson DM, Nendry WS, Vogel SF (1964) Central ganglioneuroma — A case study using electron microscopy. J Neuropathol Exp Neurol 23:692–705
Roth A, Caulet T, Pluot M, Naffioli C (1980) A propos d'une observation de paragangliome gangliocytique a localisation duodenale. Arch Anet Cytol Pathol 28:109–112
Rubinstein LJ (1972) Tumors of the central nervous system. In: AFIP Atlas of tumor pathology, fasc 6. AFIP, Washington, DC
Rubinstein LJ, Herman MM (1972) A light and electron microscopic study of a temporal lobe ganglioglioma. J Neurol Sci 16:27–48
Russell DS, Rubinstein LJ (1977) Paraganglioma (chemodectoma) of the conus medullaris-filum terminale. In: Russell DS, Rubinstein LJ (eds) Pathology of tumours of the nervous system. Williams & Wilkins, Baltimore, pp 269–270
Taylor HB, Helwig EG (1962) Benign nonchromaffin paragangliomas of the duodenum. Virchows Arch A [Pathol Anat] 355:356–366
Tomiyasu U, Hirano A, Zimmerman HM (1973) Fine structure of human pituitary adenoma. Arch Pathol (Chic) 95:287–292
Watzka M (1943) Die Paraganglien. In: von Möllendorf W (Hrsg) Handbuch der mikroskopischen Anatomie des Menschen, Bd VI/4. Springer, Berlin, S 262–308
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Schmitt, H.P., Wurster, K., Bauer, M. et al. Mixed chemodectoma-ganglioneuroma of the conus medullaris region. Acta Neuropathol 57, 275–281 (1982). https://doi.org/10.1007/BF00692183
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DOI: https://doi.org/10.1007/BF00692183