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Mixed chemodectoma-ganglioneuroma of the conus medullaris region

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Summary

Report of a 33-year-old man with a yearlong historory of low-back pain radiating into the left leg. Neurologic examination upon admission tto the hospital revealed a spinal compression syndrome at the lovel L5. Laminectomy at L4/5 revealed an encapsulated intradural tumor measuring 4×2.5×2.5 cm. The tumor was attached to the dorsal root L4 and extended downward to the conus region. Light and electron microscopy revealed features mostly consistent with a mixed chemodectoma and ganglioneuroma.

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References

  1. Alphen HAM van, Bellot SM, Stam FC (1977) Paraganglioma of cauda equina. Clin Neurol Neurosurg 79:316–322

    Google Scholar 

  2. Andrew A (1976) APUD cells, apudomas and the neural crest. S Afr Med J 50:890–898

    Google Scholar 

  3. Beltrami CA, Montironi R, Cinti S (1980) Gangliocytic paraganglioma of the duodenum: case report. Tumori 66:637–641

    Google Scholar 

  4. Beltran GE, Leiderman E, Stuckey WJ Jr, Ferrans VJ, Mogabcab WJ (1969) Metastatic ganglioneuroblastoma: ultrastructural, histochemical, and virological studies in a case. Cancer 24:552–559

    Google Scholar 

  5. Bílbao JM, Horvath E, Kovacs K, Singer W, Hudson AR (1978) Intrasellar paraganglioma associated with hypopituitarism. Arch Pathol Lab Med 102:95–98

    Google Scholar 

  6. Burger PC, Vogel FS (1976) Surgical pathology of the nervous system and its coverings. Wiley & Sons, New York London Sydney Toronto

    Google Scholar 

  7. Ciappetta P, Perrino G, Albrizio M (1980) Functionless nonchromaffin retroperitoneal paraganglioma causing cauda equina compression. Acta Neurochir (Wien) 53:181–186

    Google Scholar 

  8. Duncan DK, McDonald JR (1951) Chemodectoma (‘nonchromaffin paraganglioma’). Am J Clin Pathol 21:515–520

    Google Scholar 

  9. Glenner GG, Grimley PM (1974) Tumors of the extra-adrenal paraganglion system (including chemoreceptors). In: AFIP Atlas of tumor pathology, fasc 9. AFIP, Washington, DC

    Google Scholar 

  10. Grimley PM, Glenner GG (1967) Histology and ultrastructure of carotid body paragangliomas. Comparison with the normal gland. Cancer 20:1473–1488

    Google Scholar 

  11. Haber S (1964) Retroperitoneal and mediastinal chemodectoma. Am J Roentgenol 92:1029–1041

    Google Scholar 

  12. Helpap B (1978) Extraadrenale Paraganglien und Paragangliome. In: Bargmann W, Doerr W (Hrsg) Normale und pathologische Anatomie, Bd 37. Thieme, Stuttgart

    Google Scholar 

  13. Hitano A (1978) Some contributions of electron microscopy to the diagnosis of brain tumors. Acta Neuropathol (Berl) 43:119–128

    Google Scholar 

  14. Hirano A (1981) A guide to neuropathology. Igaku Shoin, New York Tokyo

    Google Scholar 

  15. Horoupian DS, Kerson LA, Saiontz H, Valsamis M (1974) Paraganglioma of cauda equina. Clinicopathologic and ultrastructural studies of an unusual case. Cancer 33:1337–1348

    Google Scholar 

  16. Kepes JJ, Zaccharias DL (1971) Gangliocyctic paragangliomas of the duodenum. A report of two cases with light and electron microscopic examination. Cancer 27:61–70

    Google Scholar 

  17. Kohn A (1900) Über den Bau und die Entwicklung der sog. Carotisdrüse. Arch Mikr Anat 56:81–148

    Google Scholar 

  18. Lagacé R, Delage C, Gagné F (1978) Paraganglioma of the filum terminale. Can J Neurol Sci 5:257–260

    Google Scholar 

  19. Lauzon A, Cadotte M (1972) Paragangliome gangliocytaire du duodenum. Un Med Can 101:1584–1586

    Google Scholar 

  20. Lerman RJ, Kaplan ES, Daman L (1972) Ganglioneuroma-paraganglioma of the intradural filum terminale. J Neurosurg 36:652–658

    Google Scholar 

  21. Hena JF, Hirano A, Rubin RC (1979) Paraganglioma in the cauda equina region. Acta Neuropathol (Berl) 46:235–237

    Google Scholar 

  22. Maier HC, Humphreys GE (1958) Intrathoracic pheochromocytoma. J Thorac Surg 87:369–373

    Google Scholar 

  23. Miller CA, Torack RM (1970) Secretory ependymoma of the filum terminale. Acta Neuropathol (Berl) 15:240–250

    Google Scholar 

  24. Pearse AGE (1961) Histochemistry. Theoretical and applied, 2nd edn. Churchill, London

    Google Scholar 

  25. Pearse AGE (1969) The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic and pathologic implications of the concept. J Histochem Cytochem 17:303–313

    Google Scholar 

  26. Reyes MG, Fresco R, Bruetman ME (1977) Mediastinal paraganglioma causing spinal cord compression. J Neurol Neurosurg Psychiatry 40:276–279

    Google Scholar 

  27. Robertson DM, Nendry WS, Vogel SF (1964) Central ganglioneuroma — A case study using electron microscopy. J Neuropathol Exp Neurol 23:692–705

    Google Scholar 

  28. Roth A, Caulet T, Pluot M, Naffioli C (1980) A propos d'une observation de paragangliome gangliocytique a localisation duodenale. Arch Anet Cytol Pathol 28:109–112

    Google Scholar 

  29. Rubinstein LJ (1972) Tumors of the central nervous system. In: AFIP Atlas of tumor pathology, fasc 6. AFIP, Washington, DC

    Google Scholar 

  30. Rubinstein LJ, Herman MM (1972) A light and electron microscopic study of a temporal lobe ganglioglioma. J Neurol Sci 16:27–48

    Google Scholar 

  31. Russell DS, Rubinstein LJ (1977) Paraganglioma (chemodectoma) of the conus medullaris-filum terminale. In: Russell DS, Rubinstein LJ (eds) Pathology of tumours of the nervous system. Williams & Wilkins, Baltimore, pp 269–270

    Google Scholar 

  32. Taylor HB, Helwig EG (1962) Benign nonchromaffin paragangliomas of the duodenum. Virchows Arch A [Pathol Anat] 355:356–366

    Google Scholar 

  33. Tomiyasu U, Hirano A, Zimmerman HM (1973) Fine structure of human pituitary adenoma. Arch Pathol (Chic) 95:287–292

    Google Scholar 

  34. Watzka M (1943) Die Paraganglien. In: von Möllendorf W (Hrsg) Handbuch der mikroskopischen Anatomie des Menschen, Bd VI/4. Springer, Berlin, S 262–308

    Google Scholar 

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Schmitt, H.P., Wurster, K., Bauer, M. et al. Mixed chemodectoma-ganglioneuroma of the conus medullaris region. Acta Neuropathol 57, 275–281 (1982). https://doi.org/10.1007/BF00692183

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