Abstract
In a retrospective study, 22 patients treated surgically for solitary or multiple myeloma between 1980 and 1993 were analysed. The main complaint was pain. A fracture was observed in 7 cases and motor-sensory impaired neurology due to spinal compression in 3. Apart from incisional biopsies, tumour resections, reductions (with and without stabilization by osteosynthesis) and endoprotheses were performed either at the extremities or on the spine. In addition, radiation and chemotherapy were included in the therapeutical concept. Early mobilization was achieved in all cases, and the 5-year survival rate (Kaplan-Meier method) was 48%. The results presented in this study demonstrate that a variety of surgical interventions can be of importance in the treatment of myeloma of the bone, ranging from biopsy or even curative resections in selected cases to endoprosthetic replacement. Thus, good functional results can be achieved and maintained over often long survival times.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bataille R (1982) Localized plasmacytomas. Clin Haematol 11:113–121
Bataille R, Sany J (1981) Solitary myeloma: clinical and prognostic features of a review of 114 cases. Cancer 48:845–851
Brinch L, Hannisdal E, Abrahamsen AF, Kvaloy S, Langbolm R (1990) Extramedullary plasmacytomas and solitary plasma-cell tumours of bone. Eur J Haematol 44:131–134
Campanacci M (1990) Plasmacytoma. In: Campanacci M, Bertoni F, Bacchini P (eds) Bone and soft tissue tumours. Springer, Berlin Heidelberg New York, pp 559–574
Frassica DA, Frassica FJ, Schray MF, Sim FH, Kyle RA (1989) Solitary plasmacytoma of bone: Mayo Clinic ex-perience. Int J Radiat Oncol Biol Phys 16:43–48
Ganjoo RK, Malpas JS, Plowman PN (1993) Solitary plas-macytoma of bone — a rare disorder with an unusual evolution. Postgrad Med J 69:153–154
Hosten N von, Schörner W, Neumann K, Sander B, Oertel J, Kirsch A, Schubeus P, Cordes M, Felix R, Huhn D (1992) Magnetresonanztomographische Screeninguntersuchungen des Knochenmarkes mit Gradientenecho-Sequenzen. Fortschr Röntgenstr 157:53–58
Jónsson B, Sjöström L, Jónsson H, Karlström G (1992) Surgery for multiple myeloma of the spine. A retrospective analysis of 12 patients. Acta Orthop Scand 63:192–194
Kivioja AH, Karaharju EO, Elomaa I, Böhling TO (1992) Surgical treatment of myeloma of bone. Eur J Cancer 28A:1865–1869
Kyle RA (1975) Multiple myeloma. Review of 869 cases. Mayo Clin Proc 50:29–40
Löfvenberg R, Löfvenberg EB, Ahlgren O (1990) A case of occipitocervical fusion in myeloma. Acta Orthop Scand 61:81–83
Martin NS, Williamson J (1970) The role of surgery in the treatment of malignant tumours of the spine. J Bone Joint Surg [Br] 52:227–237
McLain RF, Weinstein JN (1989) Solitary plasmacytomas of the spine: a review of 84 cases. J Spinal Disord 2:69–74
Pasqualetti P, Casale R, Collacciani A, Abruzzo BP, Colatonio D (1990) Multiple myeloma: relationship between survival and cellular morphology. Am J Hematol 33:145–147
Pasqualetti P, Casale R, Collacciani A, Colantonio D (1991) Prognostic factors in multiple myeloma: a new staging system based on clinical and morphological features. Eur J Cancer 27:1123–1126
Vogler JB, Murphy WA (1988) Bone marrow imaging. Radiology 168:679–693
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Dürr, H.R., Kühne, JH., Hagena, FW. et al. Surgical treatment for myeloma of the bone. Arch Orthop Trauma Surg 116, 463–469 (1997). https://doi.org/10.1007/BF00387578
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00387578