This is a preview of subscription content, log in via an institution to check access.
References
Berger CL, Warburton D, Raafat J, Logerfo P, Edelson RL (1979) Cutaneous T-cell lymphoma: neoplasm of T-cells with helper activity. Blood 53:642–651
Broder S, Edelson RL, Lutzner MA, Nelson DL, Mac Dermott RP, Drum ME, Goldman CK, Meade BD, Waldmann RA (1976) The Sézary syndrome: a malignant proliferation of helper T-cells. J Clin Invest 58:1297–1306
Broome JD, Zucker-Franklin D, Weiner MS, Bianco C, Nussenzweig V (1973) Leukemic cells with membrane properties of thymus-derived (T) lymphocytes in a case of Sézary's syndrome: morphological and immunologic studies. Clin Immunol Immunopathol 1:319–324
Brouet JC, Flandrin G, Seligmann N (1973) Indications of the thymus-derived nature of the proliferating cells in six patients with Sezary's syndrome. New Engl J Med 289:341–344
Claudy A (1974) The immunological identification of the Sézary cell. Br J Dermatol 91:597
Crossen PE, Mellor JEL, Fincey AG, Ravich RBM, Vincent PP, Gunz FW (1971) The Sézary syndrome. Am J Med 50:24–34
Graham RC, Karnovsky MJ (1966) The early stages of absorption of injected horseradish peroxidase in the proximal tubules of mouse kidney. Ultrastructural cytochemistry by a new technique. J Histochem Cytochem 14:291
Hopper JE Haren JM (1980) Studies on a Sézary lymphocyte population with T-suppressor activity. Clin Immunol Immunopathol 17:43–54
Kansu E, Hauptman SM (1979) Suppressor cell population in Sézary syndrome. Clin Immunol Immunopathol 12:341–350
Kohler G, Milstein C (1975) Continuous cultures of fused cells secreting antibody of predetermined specificity. Nature 256:495–497
Kourilsky PM, Silvestre D, Levy JP, Dausset J, Nicolai MG, Senik A (1971) Immunoferritin study of the distribution of HLA antigens on human blood cells. J Immunol 106:454–466
Kung PC, Goldstein G, Reinherz EL, Schlossman SF (1979) Monoclonal antibodies defining distinctive human T-cell surface antigens. Science 206:347–349
Lawrence EC, Broder S, Jaffe ES, Braylan RC, Dobbins WO, Young RC, Waldmann TA (1978) Evolution of a lymphoma with helper T-cell characteristics in Sézary syndrome. Blood 52:481–492
Laroche L, Bach JF (1981) T-cell imbalance in non leukemic and leukemic cutaneous lymphoma defined by monoclonal antibodies. Clin Immunol Immunopathol (in press)
Reinherz EL, Kung PC, Goldstein G, Levey RH, Schlossman SF (1980) Discrete stages of human intrathymic differentiation: analysis of normal tymocytes and leukemic lymphoblasts of T-lineage. Proc Nat Acad Sci 77:1588
Schmitt D, Brochier J, Revillard JP, Thivolet J (1976) Ultrastructural identification of human tonsil T-lymphocytes by peroxidase-conjugated anti-HTLA serum. Experientia 32:1208–1209
Schmitt D, Viac J, Brochier J, Thivolet J (1976) Thymus-derived origin of Sézary cells demonstrated by peroxidase-conjugated anti-HTLA serum. Acta Derm Venereol (Stockh) 56:489–497
Thivolet J, Fulton R, Souteyrand P, Gaucherand M, Claudy A (1981) Sézary syndrome: a relative increase in T helper cells as demonstrated by monoclonal antibodies. J Invest Dermatol (in press)
Zucker-Franklin D (1976) Thymus-dependent lymphocytes in lymphoproliferative disorders of the skin. (Sézary syndrome and mycosis fungoïdes). J Invest Dermatol 67:412–418
Author information
Authors and Affiliations
Additional information
Supported by a grant from the Institut National de la Santé et de la Recherche Médicale (INSERM-ATP 67 78 99 no. 23) and DGRST (grant no. 8070308)
Rights and permissions
About this article
Cite this article
Schmitt, D., Thivolet, J., Souteyrand, P. et al. Helper phenotype of the Sézary cell: Direct ultrastructural evidence using monoclonal antibodies. Arch Dermatol Res 270, 487–490 (1981). https://doi.org/10.1007/BF00403794
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00403794