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Der immunologisch bedingte Abort — Diagnose und Therapie

Immunological factors in recurrent spontaneous abortion

  • Geburtshilfe, Materno-Fetale Medizin
  • Immunologie der Schwangerschaft «Habitueller» Abort
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Summary

As etiological factors responsible for repeated miscarriages disturbances of the maternal-fetal immunoregulation are involved. Diagnostic aspects of the immunobiology of abortion and the clinical management of habitual abortion by immunotherapy are discussed.

Zusammenfassung

In der Schwangerschaft trägt die Mutter ein mit eigener Antigenität ausgestattetes, wachsendes Transplantat, den Embryo oder Fetus. Bei regelrechtem Schwangerschaftsverlauf bildet das maternale Immunsystem blokkierende Faktoren, so daß der Embryo einer Abstoßung durch den mütterlichen Organismus entgeht. Störungen des immunologischen Gleichgewichtes zwischen mütterlichem Immunsystem und Embryo führen zum immunologisch bedingten Abort. Die Diagnostik besteht in dem fehlenden Nachweis schwangerschafts-schützender Faktoren. Neuerdings kann bei den Patientinnen mit immunologisch bedingter Abortneigung eine spezifische Immuntherapie zur Abortprophylaxe durchgeführt werden.

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Authors and Affiliations

  1. Universitäts-Frauenklinik Düsseldorf, Düsseldorf, Deutschland

    M. von Ditfurth & W. Distler

  2. Institut für Blutgerinnungswesen, Universität Düsseldorf, Düsseldorf, Deutschland

    B. M. E. Kuntz

  3. Institut für Immungenetik, Universitätsklinikum Essen, Essen, Deutschland

    U. Kuhn

Authors
  1. M. von Ditfurth
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  2. B. M. E. Kuntz
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  3. U. Kuhn
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  4. W. Distler
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von Ditfurth, M., Kuntz, B.M.E., Kuhn, U. et al. Der immunologisch bedingte Abort — Diagnose und Therapie. Arch Gynecol Obstet 245, 149–154 (1989). https://doi.org/10.1007/BF02417219

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  • DOI: https://doi.org/10.1007/BF02417219

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