Summary
Two patients with a trophoblastic tumour (one with an invasive mole and one with a choriocarcinoma) had early pregnancy factor (EPF; detected by rosette inhibition test) in serum. In both cases the EPF already disappeared during surgery which suggests that EPF could be a useful and sensitive tumour marker if laboratory technology for its detection could be improved.
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Bojahr, B., Straube, W. & Römer, T. Early pregnancy factor (EPF) as tumour marker in two patients with trophoblastic tumour. Arch Gynecol Obstet 252, 215–218 (1993). https://doi.org/10.1007/BF02426361
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DOI: https://doi.org/10.1007/BF02426361