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Sclerotic changes around the endolymphatic sac in human temporal bones

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Summary

We used light microscopy to study 87 human temporal bones (from 47 cases) with no known otological disorders, and found that certain cases had sclerotic changes around the endolymphatic duct and sac. Changes included fibrosis, hyalinization, psammoma formation, and thickened vascular walls. The findings were subjected to statistical analysis, which indicated that most of the changes could be positively correlated with increases in age.

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Author notes

  1. Noboru Sakai

    Present address: Hokkaido University School of Medicine, Sapporo, Japan

  2. Kazuhiro Ohashi

    Present address: Osaka City University Medical School, Osaka, Japan

Authors and Affiliations

  1. Department of Otorhinolaryngology and Communicative Sciences, Baylor College of Medicine, One Baylor Plaza, 77030, Houston, TX, USA

    Noboru Sakai, Makoto Igarashi, Kazuhiro Ohashi & Masanori Ishii

Authors
  1. Noboru Sakai
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  2. Makoto Igarashi
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  3. Kazuhiro Ohashi
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  4. Masanori Ishii
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Additional information

Supported in part by NINCDS grant NS-10940

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Sakai, N., Igarashi, M., Ohashi, K. et al. Sclerotic changes around the endolymphatic sac in human temporal bones. Arch Otorhinolaryngol 242, 315–320 (1985). https://doi.org/10.1007/BF00453556

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  • DOI: https://doi.org/10.1007/BF00453556

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