Summary
Distribution of the serotonin nerve fibers in the neurohypophysis of adult cats was demonstrated using the peroxidase-antiperoxidase method. The serotonin nerve fibers were distributed in the internal and external layers of the infundibulum, terminating on the wall of the capillary loops and the outer surface of the external layer. A small number of the fibers scattered about in the posterior lobe penetrated the intercellular spaces in the intermediate lobe.
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References
Beaudet A, Descarries L (1979) Radioautographic characterization of a serotonin-accumulating nerve cell group in adult rat hypothalamus. Brain Res 160:231–243
Björklund A, Falck B (1967) Pituitary monoamines of the cat with special reference to the presence of an unidentified monoamine-like substance in the adenohypophysis. Z Zellforsch 93:254–264
Björklund A, Falck B, Nobin A, Stenevi U (1974) Organization of the dopamine and noradrenaline innervations of the median eminence — pituitary region in the rat. In: Knowles F, Vollrath L (eds) Neurosecretion — The final neuroendocrine pathway. Springer, Berlin Heidelberg New York, pp 209–222
Björklund A, Moore RY, Nobin A, Stenevi U (1973) The organization of tubero-hypophyseal and reticulo-infundibular catecholamine neuron systems in the rat brain. Brain Res 51:171–191
Calas A, Alonso G, Arnauld E, Vincent JD (1974) Demonstration of indolaminergic fibers in the median eminence of the duck, rat and monkey. Nature 250:241–243
Carlsson A, Falck B, Hillarp NÅ (1962) Cellular localization of brain monoamines. Acta Physiol Scand 56: Suppl 196
Chan-Palay V (1977) Indoleamine neurons and their processes in the normal rat brain and in chronic diet-induced thiamine deficiency demonstrated by uptake of 3H-serotonin. J Comp Neurol 176:467–494
Descarries L, Beaudet A (1978) The serotonin innervation of adult rat hypothalamus. In: Vincent JD, Kordon C (eds) Cell biology of hypothalamic neurosecretion. Coll Internat CNRL, Vol. 80, pp 35–153
Fuxe K (1963) Cellular localization of monoamines in the median eminence and in the infundibular stem of some mammals. Acta Physiol Scand 58:383–384
Fuxe K (1964) Cellular localization in the median eminence and infundibular stem of some mammals. Z Zellforsch 61:710–724
Fuxe K, Hökfelt T, Agnanti L, Loftrom A, Everitt B, Johansson O, Jonsson G, Wuttke W, Goldstein M (1976) Role of monoamines in the control of gonadotropin secretion. In: Kumar A (ed) Neuroendocrine regulation of fertility. S Karger, Basel, pp 124–140
Jonsson G, Fuxe K, Hökfelt T (1972) On the catecholamine innervation of the hypothalamus, with special reference to the median eminence. Brain Res 40:271–281
Martin WR, Sloan JW, Christian ST, Clements TH (1972) Brain levels of tryptamine. Psychopharmacologia 24:331–346
Piezzi RS, Larin F, Wurtman RJ (1970) Serotonin, 5-hydroxy-indoleacetic acid (5-HIAA), and monoamine oxidase in the bovine median eminence and pituitary gland. Endocrinology 86:1460–1462
Piezzi RS, Wurtman RJ (1970) Pituitary serotonin content: Effect of melatonin or deprivation of water. Science 169:285–286
Saavedra JM (1977) Distribution of serotonin and synthesizing enzymes in discrete areas of the brain. Fed Proc 36:2134–2141
Saavedra JM, Palkovits M, Brownstein MJ, Axelrod J (1974) Serotonin distribution in the nuclei of the rat hypothalamus and preoptic region. Brain Res 77:157–165
Steinbusch HWM (1981) Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. Neuroscience 6:557–618
Steinbusch HWM, Nieuwenhuys R (1981) Localization of serotonin-like immunoreactivity in the central nervous system and pituitary of the rat, with special references to the innervation of the hypothalamus. In: Haber B (ed) Advance in experimental medical biology, Vol 133. Plenum Press, New York
Takeuchi Y, Kimura H, Sano Y (1982) Immunohistochemical demonstration of the distribution of serotonin neurons in the brainstem of the rat and cat. Cell Tissue Res 224:247–267
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Sano, Y., Takeuchi, Y., Matsuura, T. et al. Immunohistochemical demonstration of serotonin nerve fibers in the cat neurohypophysis. Histochemistry 75, 293–299 (1982). https://doi.org/10.1007/BF00496732
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DOI: https://doi.org/10.1007/BF00496732