Summary
An X chromosome specific nucleic acid probe was used to study the positions of the X chromosomes in leukocyte nuclei by in situ hybridization to smears of peripheral blood. This autoradiographic approach allowed the first direct demonstration of the presence of X chromosomal material in the drumstick-like structures of female polymorphonuclear leukocytes.
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In honour of Prof. P. van Duijn
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Hochstenbach, P.F.R., Scheres, J.M.J.C., Hustinx, T.W.J. et al. Demonstration of X chromatin in drumstick-like nuclear appendages of leukocytes by in situ hybridization on blood smears. Histochemistry 84, 383–386 (1986). https://doi.org/10.1007/BF00482967
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DOI: https://doi.org/10.1007/BF00482967