Skip to main content
SpringerLink
Log in

The chicken NKX2.8 homeobox gene: A novel member of the NK-2 gene family

  • ORIGINAL ARTICLE
  • Published:
Development Genes and Evolution Aims and scope Submit manuscript

Abstract

 We have isolated the chicken homeobox gene NKX2.8, which represents a novel member of the NK-2 gene family. Besides the homeodomain, the NKX2.8 protein contains two other conserved sequences, a TN and an NK2 domain. NKX2.8 is expressed in the ventral foregut, the developing heart, in the epithelial layers of the branchial arches and in the dorsal mesocardium. Thus, its expression overlaps partially, but also differs significantly from another chicken tinman orthologue, the NKX2.5 gene. It is suggestive that NKX2.8 and NKX2.5 play a cooperative role in early heart development.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Max-Planck-Institut für biophysikalische Chemie, Am Fassberg, D-37077 Göttingen, Germany, , , , , , DE

    Thomas Boettger, Stefan Stein & M. Kessel

Authors
  1. Thomas Boettger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stefan Stein
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Kessel
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 28 January 1997 / Accepted: 8 February 1997

Rights and permissions

Reprints and permissions

About this article

Cite this article

Boettger, T., Stein, S. & Kessel, M. The chicken NKX2.8 homeobox gene: A novel member of the NK-2 gene family. Dev Gene Evol 207, 65–70 (1997). https://doi.org/10.1007/s004270050092

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s004270050092

Search

Navigation