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Cellular differentiations and structural characteristics in nasopharyngeal angiofibromas

An electron-microscopic study

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Summary

An electron-microscopic study of 9 nasopharyngeal angiofibromas was performed in order to elucidate the ultrastructural characteristics. Stromal fibroblasts and proliferating cells of the microvasculature were found. The stromal fibroblasts were subdivided into 3 different groups: (1) “classical” fibroblasts, (2) fibroblasts with histiocytelike features, and (3) fibroblasts with myoid features. By proliferation the cells of the capillary vessels change into stromal cells. A particular pattern of nuclei and dense intranuclear granules is only found in stromal fibroblasts. Consequently fibroblasts as well as cells of the microvasculature contribute to the pool of tumor cells.

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Authors and Affiliations

  1. Institute of Pathology and Clinic of Oto-Rhino-Laryngology of the Friedrich-Schiller-University of Jena, DDR

    Dankwart Stiller, Detlef Katenkamp & Klaus Küttner

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  1. Dankwart Stiller
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  2. Detlef Katenkamp
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  3. Klaus Küttner
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Stiller, D., Katenkamp, D. & Küttner, K. Cellular differentiations and structural characteristics in nasopharyngeal angiofibromas. Virchows Arch. A Path. Anat. and Histol. 371, 273–282 (1976). https://doi.org/10.1007/BF00433074

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