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B-cell nature malignant lymphoma probably caused by EB-virus infection

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Summary

In cells in a haemopericardium associated with a B-cell malignant lymphoma, immature herpes type virus particles were found by electron microscopy. Epstein-Barr virus associated nuclear antigen (EBNA) and virus capsid antigen (VCA) were also found, both in the tumor cells, in the bloody pericardial fluid and in cultivated cells. Serological studies revealed high anti-toxoplasma antibody levels both in the pericardial fluid and in serum. Both EB virus and toxoplasma infections are assumed to have played an important role on the pathogenesis of the present case.

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Authors and Affiliations

  1. Department of Pathology, Niigata University School of Medicine, Niigata, Japan

    Iwao Emura, Yoshihisa Ohnishi & Syoichi Oboshi

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  1. Iwao Emura
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  2. Yoshihisa Ohnishi
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  3. Syoichi Oboshi
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Emura, I., Ohnishi, Y. & Oboshi, S. B-cell nature malignant lymphoma probably caused by EB-virus infection. Virchows Arch. A Path. Anat. and Histol. 378, 321–328 (1978). https://doi.org/10.1007/BF00465598

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  • DOI: https://doi.org/10.1007/BF00465598

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