Summary
The anatomy of the cecum of the domesticated guinea pig (Cavia apera f. procellus) was investigated at the macroscopic and microscopic levels. In situ observations, injections of the blood vascular system and the preparation of dried specimens were made to elucidate the macroscopic anatomy of the cecum. The complex mesenterial situation in the abdomen was also investigated.
The guinea-pig intestinal tract is particularized by the presence of the voluminous teniated cecum, which lacks an appendix vermiformis. The stomach is relative small and simple; the large intestine does not possess teniae. Seen with the scanning electron microscope the surface topography of the cecal wall shows a pattern of irregular mounds and crevasses. The former are made up of raised ridges, often in circular or looped profiles. Correlated light microscopic observation revealed an irregularity of the mucosal surface consisting of protrusions into the cecal lumen, the circular and looped configurations of the scanning microscope image representing the entry into crypts at the light-microscopic level. The close association of bacteria to the mucosal surface is striking. Observed with the transmission electron microscope this close association takes the form of an intermicrovillar location of the bacteria.
The present observations are compared to those made on other rodents and with respect to the dietary habit of the guinea pig.
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References
Behmann H (1973) Vergleichend- und funktionell-anatomische Untersuchungen am Caecum und Colon myomorpher Nagetiere. Z wiss Zool 186:173–294
Bond JH, Levitt MD (1976) Fate of soluble carbohydrate in the colon of rats and man. J Clin Invest 57:1158–1164
Cheng KJ, Costerton JW (1980) Adherent rumen bacteria-their role in the digestion of plant material, urea and epithelial cells. In: Digestion physiology and metabolism in ruminants. MTP Press Ltd. Lancaster England
Davis CP, Mulcahy D, Takeuchi A, Savage DC (1972) Location and description of spiral-shaped microorganisms in the normal rat caecum. Infect Immun 6:184–192
Eberhard IH, McNamara J, Pearse RJ, Southwell IA (1975) Ingestion and excretion of Eucalyptus pinctata and its essential oil in the koala, Phascolarctos cinereus (Goldfuss). Aust J Zool 23:169–179
Gabella G (1981) On the musculature of the gastro-intestinal tract of the guinea-pig. Anat Embryol 163:135–156
Gorgas M (1967) Vergleichend-anatomische Untersuchungen am Magen-Darm-Kanal der Sciuromorpha Hystricomorpha and Caviomorpha (Rodentia). Z wiss Zool 175:237–404
Janis C (1976) The evolutionary strategy of the Equidae and the origins of rumen and cecal digestion. Evolution 30:757–774
Just A, Jørgensen H, Fernández JA (1981) The digestive capacity of the caecum-colon and the value of the nitrogen absorbed from the hind gut for protein synthesis in pigs. Br J Nutr 46:209–219
Koopmann JP, Kennis HM (1979) Characterization of anaerobic cecal bacteria of mice. Z Versuchstierkd 21:185–191
Koopmann JP, Kennis HM, van Druten JAM (1979) The role of the cecum in the gastrointestinal colonization resistance in mice. Z Versuchstierkd 21:192–196
Krause R (1921) Mikroskopische Anatomie der Wirbeltiere in Einzeldarstellung. I. Säugetiere. Berlin u. Leipzig
Langer P (1979) Functional gastric anatomy of macropod marsupials. Ann Rech Vet 10:(2/3)476–579
Leach WD, Lee A, Stubbs RP (1973) Localization of bacteria in the gastrointestinal tract: a possible explanation of intestinal spirochaetosis. Infect Immun 7961–972
Leng E (1978) Absorption of inorganic ions and volatile fatty acids in the rabbit caecum. Br J Nutr 40:509–519
Loeschke K (1975) Intestinale Adaptation der Elektrolyt- und Wasserresorption. Fortschr Med 93:1613–1615
Lungershausen J (1940) Zur Anatomie des Verdauungsapparates von Lepus timidus Schreb. Inaugural-Dissertation Leipzig 1939. Z Anat Entw Gesch 110:22–246
McKenzie, RA (1978) The caecum of the Koala, Phascolarctos cinereus: Light, Scanning and transmission electron microscopic observations on its epithelium and flora. Aust J Zool 26:249–256
Mitchell C (1905) On the intestinal tract of mammals. Trans Zool Soc Lond (XVII 1903-1906) 437–536
Mottaz P, Worbe JF (1977) Transfert des acides gras volatile dans la paroi du caecum isolé de rat. Comptes rend séances Soc biol 171:375–380
Olszewski A (1978a) Competitive inhibition and exchange transport between arginine and lysine in the process of absorption from the caecum in pigs. Acta Physiol Pol 29:161–165
Olszewski A (1978b) Interrelationships between amino acids absorbed from the isolated pig caecum in situ. Acta Physiol Pol 29:168–176
Olszewski A, Buraczewski S (1978) Absorption of amino acids in isolated pig caecum in situ. Acta Physiol Pol 29:67–77
Owen RL, Nemanic P (1978) Antigen processing structures of the mammalian intestinal tract: an SEM study of lymphoepithelial organs. Scanning Electron Microscopy Vol II SEM Inc AMF. O'Hare III 60666 USA
Parker D (1976) The measurment of production rates of volatile fatty acids in the caecum of the conscious rabbit. Br J Nutr 36:61–70
Puget A, Voisin MC (1973) Anatomie microscopique de l'appareil digestif d'Ochotona rufescens rufescens. Acta Anat 84:267–281
Rayssiguier Y, Remesy C (1977) Magnesium absorption in the caecum of rats related to volatile fatty acid production. Ann Rech Vét 8:105–110
Rérat A (1977) Digestion and absorption of carbohydrates and nitrogenous matter in the hindgut of the omnivorous nonruminant animal. J Anim Sci 46:1808–1837
Sakata T, von Engelhardt W (1981) Luminal mucin in the large intestine of mice, rats and guinea-pigs. Cell Tissue Res215:629–635
Savage DC, Dubos R, Schaedler RW (1968) The gastrointestinal epithelium and its autochtonous bacterial flora. J Exp Med 127:97–110
Snipes RL (1978) Anatomy of the rabbit cecum. Anat Embryol 155:57–80
Snipes RL (1979a) Anatomy of the cecum of the vole, Microtus agrestis. Anat Embryol 157:181–203
Snipes RL (1979b) Anatomy of the cecum of the dwarf hamster (Phodopus sungorus). Anat Embryol 157:329–346
Snipes RL (1981) Anatomy of the cecum of the laboratory mouse and rat. Anat Embryol 162:455–474
Snipes RL (1982) Anatomy of the cecum of the gerbil Meriones unguiculatus (Mammalia, Rodentia, Cricetidae). Zoomorphology (in press)
Snipes RL, Clauss W, Weber A, Hörnicke H (1982) Structural and functional differences in various divisions of the rabbit colon. Cell Tissue Res 225:331–346
Toner PG, Carr KE, Wyburn GM (1971) The digestive system—an ultrastructural atlas and review. Butterworths London
Vorontsov NN (1960) The ways of food specializations and evolution of the alimentary system in Muroidea. symp Ther Proc Internat Symp Meth Mammal Invest Brono Prag 360–377
Vorontsov NN (1963) Die Ungleichmäßigkeit der Tempi der Umgestaltung der Organe und das Prinzip der Kompensation der Funktionen. Zool J 9:1289–1305
Wille KH (1975) Über die Schleimhautoberfläche des Blinddarmes einiger Haussäuger. Eine raster-elektronenmikroskopische Untersuchung. Zentralbl Veterinärmed (C) 4:265–273
Ziswiler V (1981) Spezialisation im Ernährungs- und Verdauungssystem der Wirbeltiere: Möglichkeiten und Limiten der Adaption. Revue Suisse Zool 88:829–834
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Spines, R.L. Anatomy of the guinea-pig cecum. Anat Embryol 165, 97–111 (1982). https://doi.org/10.1007/BF00304586
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DOI: https://doi.org/10.1007/BF00304586