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Effects of Fusobacterium necrophorum on the mesenteric microcirculation of guinea pigs

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Abstract

Thrombi formation was demonstrated in mesenteric microcirculation of guinea pigs inoculated with Fusobacterium necrophorum and the bacterial hemagglutinin (HA). The thrombi were initially observed in venules and later, in arterioles. Immunofluorescence study revealed that the HA bound to the thrombi in the microcirculation. These results indicate that thrombosis is an early step in the pathogenesis of necrosis.

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Authors and Affiliations

  1. Departments of Veterinary Microbiology Faculty of Agriculture, Yamaguchi University, 753, Yamaguchi, Japan

    M. Kanoe & M. Yamanaka

  2. Departments of Veterinary Pathology, Faculty of Agriculture, Yamaguchi University, 753, Yamaguchi, Japan

    M. Inoue

Authors
  1. M. Kanoe
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  2. M. Yamanaka
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  3. M. Inoue
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Kanoe, M., Yamanaka, M. & Inoue, M. Effects of Fusobacterium necrophorum on the mesenteric microcirculation of guinea pigs. Med Microbiol Immunol 178, 99–104 (1989). https://doi.org/10.1007/BF00203305

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  • DOI: https://doi.org/10.1007/BF00203305

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