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Complement studies in children with treated coeliac disease after gluten challenge

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Abstract

Changes of the complement components in the sera of 13 children with treated coeliac disease were studied after gluten challenge. The levels of C 1 and C 3-activator (factor B) were significantly decreased at 4 h after the challenge, as were the levels of total complement (CH 50) and the components C 1, C 4 and C 1-inactivator at 8 h. After 24 h most values returned to normal but there was another significant decrease in serum C 4 after 24 h, and for CH 50, C 1, C 2 and C 4 after 48 h.

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This study was supported by a grant from the Deutsche Forschungsgemeinschaft (Az. Op 12/11)

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Bosch, C., Becker, M., Rotthauwe, H.W. et al. Complement studies in children with treated coeliac disease after gluten challenge. Eur J Pediatr 134, 145–148 (1980). https://doi.org/10.1007/BF01846034

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  • DOI: https://doi.org/10.1007/BF01846034

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