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Regional cerebral metabolic rate for glucose in subacute sclerosing panencephalitis

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Abstract

Regional cerebral metabolic rates for glucose (rCMRglc) were measured in two cases of subacute sclerosing panencephalitis (SSPE) with different clinical courses. A marked decrease in rCMRglc was found in the cortical gray matter of a patient with rapidly developing SSPE (3.6–4.2 mg/100 g brain tissue per min). However, the rCMRglc was preserved in the caudate and lenticular nuclei of the patient (7.7 mg/100 g per min). The rCMRglc in a patient with slowly developing SSPE revealed patterns and values similar to those of the control. The rCMRglc correlated better with the neurological and psychological status of SSPE.

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Abbreviations

rCMRglc:

regional cerebral metabolic rate

SSPE:

subacute sclerosing panencephalitis

PET:

position emission tomography

[F-18]FDG:

[F-18]2-fluorodeoxyglucose

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Authors and Affiliations

  1. Department of Pediatrics, Tohoku University School of Medicine, Seiryomachi 1-1, 980, Sendai, Japan

    K. Yanai, K. Iinuma, K. Tada & S. Miyabayashi

  2. Department of Radiology and Nuclear Medicine, Research Institute for Tuberculosis and Cancer, Tohoku University, Seiryomachi 4-1, 980, Sendai, Japan

    H. Fukuda, M. Ito & T. Matsuzawa

Authors
  1. K. Yanai
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  2. K. Iinuma
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  3. K. Tada
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  4. S. Miyabayashi
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  5. H. Fukuda
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  6. M. Ito
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  7. T. Matsuzawa
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Yanai, K., Iinuma, K., Tada, K. et al. Regional cerebral metabolic rate for glucose in subacute sclerosing panencephalitis. Eur J Pediatr 146, 288–289 (1987). https://doi.org/10.1007/BF00716475

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  • DOI: https://doi.org/10.1007/BF00716475

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